Protein Alignment ERG and pnt

DIOPT Version :9

• Sequence 1: NP_001129626.1
• Gene: ERG / 2078
• HGNCID: 3446
• Length: 486
• Species: Homo sapiens
• Sequence 2: NP_524461.2
• Gene: pnt / 42757
• FlyBaseID: FBgn0003118
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 696
• Identity: 160/696 - (22%)
• Similarity: 223/696 - (32%)
• Gaps: 313/696 - (44%)

Human     7 DPAAHIKEALSVVSEDQSLFEC-------AYGTPH-LAKTEMTASSSSDYGQTSKMSPRVPQQ-D 62
            |.|||  |...:.:.:..||:.       :.|:|. |::.....:|.:..||.|.|..:..:: .
  Fly    42 DKAAH--ELFQLNAINGHLFKSPASSHLNSVGSPSILSQLNGIGNSGNHSGQVSTMRLKKNRKVT 104

Human    63 WLSQ--PPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGS--------PDTVGMN------- 110
            :||.  ....:.||.|    .::|.:   |.||::.......|        |.|.|.|
  Fly   105 FLSSLVESKNIFIKEE----PIHGCK---DLCSLSDISDHEASLEVPTALPPLTPGTNRKVNEVL 162

Human   111 ---YGSYMEEKHMPPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDG 172
               :.|:  ||.:...|:|         .||..|:.:||..||.||..|:.|..:|:..|..:.|
  Fly   163 KASFASW--EKEVQKCNIT---------KDPREWTEEHVIYWLNWAKNEFSLVSMNLDPFYKMKG 216

Human   173 KELCKMTKDDFQRLTPSYNADILLSHLHYLR---ETPLPHLTSDDV-----------------DK 217
            :.:..:.|:.|..:||.:..|||..||..|:   |.|     ::|:                 |.
  Fly   217 RAMVDLGKEKFLAITPPFTGDILWEHLDILQKDCEKP-----NEDIVHGNSFESATTASVCGSDH 276

Human   218 ALQNSPRLMHAR----------------------------------------------------- 229
            .:.|.|...||.
  Fly   277 QVANYPNETHANSNNSSINSRLSMDYVTSAGNSDNKNFHRATPHSHNGYNTSNTHDRINNSTPPQ 341

Human   230 ---------NTGGAAFIFPNTSVYPEATQRITTRPD----------------------------- 256
                     |..|:|....|.|:.|.|.|:.....:
  Fly   342 QQQSQQPTVNGSGSASSNNNNSMLPPAVQQSNNENNNTSSSNTNNSSNNNNNSGGSNNSNAGSNN 406

Human   257 --------------------LPYEPPRRSAWTG--------HGHPTPQSKAAQPS---------- 283
                                |..||..::...|        ...||..|....|:
  Fly   407 NNNNNNNINFMAAAAIFQHHLKEEPGTQNGNIGGYGGGSNSQNDPTDLSSYGLPAHLAAYGGGSG 471

Human   284 ------------------PSTVPKTEDQR------------------------------------ 294
                              .||:...:.|.
  Fly   472 SGPTGGRSSGGGGDESDYHSTISAQDHQSQQSSGGNGSGGASGGSTGNSNGYLDSSSEFYGSYAG 536

Human   295 ---------PQLDPY-----QILGPTSSRL---------ANP----------------------- 313
                     |:..||     |.:||..:.:         .:|
  Fly   537 RNRFHDGYPPEFTPYDAQSFQSMGPQPTAMDQWGAAHAHQHPAAYMSTLGLDKGLLGGYTTQGGV 601

Human   314 ----GSGQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSR 374
                |||.|||||||||||.|.:..|.|:|.|...|||:|||||||||||.||:||.|||:||||
  Fly   602 PCFTGSGPIQLWQFLLELLLDKTCQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSR 666

Human   375 ALRYYYDKNIMTKVHGKRYAYKF--DFHGIAQALQPHPPESSLYKY 418
            .|||||||||:.|..||||.|:|  |.    |.|..|.||..:.||
  Fly   667 GLRYYYDKNIIHKTAGKRYVYRFVCDL----QNLVGHTPEELVAKY 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERG	NP_001129626.1	SAM_PNT-ERG	134..208	CDD:176090	26/76 (34%)
		ETS	317..400	CDD:197710	58/84 (69%)
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879	25/79 (32%)
		ETS	609..693	CDD:197710	57/83 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810