DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Scarb1 and dsb

DIOPT Version :9

Sequence 1:	NP_001192012.1	Gene:	Scarb1 / 20778	MGIID:	893578	Length:	520	Species:	Mus musculus
Sequence 2:	NP_001097477.1	Gene:	dsb / 38252	FlyBaseID:	FBgn0035290	Length:	615	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	133/458 - (29%)
Similarity:	236/458 - (51%)	Gaps:	30/458 - (6%)

- Green bases have known domain annotations that are detailed below.

Mouse    17 LGLLFAALGVVMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYLSVYFFEVVNPNEVLNG 81
            :|::...||:::..|  ..:...:|||:|:...:||:..|:...|.....:|.:.|.||:..|.|
  Fly    85 IGIITLILGIILSSM--PWLDYFILKNLRLWNDTLSYHYWQRPGVIRLTKLYIYNVTNPDGFLRG 147

Mouse    82 QKPVVRERGPYVYREFRQKVNITFNDND-TVSFVENRSLHFQPDKSHGSESDYIVLPNILVLGGS 145
            :||.::|.||:||||..||||:.|::|: |||:...:.|.|.|:.|...::. |..|||.:|  :
  Fly   148 EKPHLQEVGPFVYREDMQKVNVKFHENNYTVSYQHKKILQFVPELSIDKDTP-ITTPNIPLL--T 209

Mouse   146 ILMESKPVSLKLMMTLA-LVTMGQ-RAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPIKGKFGLF 208
            :...|..:...|..|:: :||..| :.|:|.|..::.:||||..|...:.:.|..:....:.||.
  Fly   210 LTSLSPKLGYLLSKTISVVVTAAQFKPFINVTAEQLAFGYDDALVSLAHRFYPKHMRPMERMGLL 274

Mouse   209 VGMNNSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEQCNMINGTSGQMWAP-FMTPESSL 272
            :|.|.:.:.|.:|.||:.:..:...:|:.|||..:.:|....|..|.|:.|..:.| .:|....:
  Fly   275 LGRNGTLTEVSSVKTGMDSMDQFGYIDQLNGLDHLPHWSEPPCTSIAGSEGSFFPPRELTKSEVV 339

Mouse   273 EFFSPEACRSMKLTYNESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCPCRES-------GIQN 330
            ..:..:.||.:.|.|.||...:||....|..|:..:.:.:..|.|:    |.::       |:||
  Fly   340 HIYDKDLCRIIPLKYVESLEKDGIAADLFRLPNNSYGDSAHNPENK----CYDTSEYEPIQGLQN 400

Mouse   331 VSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIK 395
            :|.|::|||:::|:|||:.:.|.|..:|.||.|..::|..:..|.|..|:|:...|::||:|.:.
  Fly   401 ISPCQYGAPVYISNPHFFESHPDLLNSVEGLKPEREKHETYFKIQPKLGVPLEGKVRIQLNLKVT 465

Mouse   396 SVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLST-----FYTQLVLMPQVLHYAQYVLLGLGGLL 455
            ..|.:.........|.|::|.|:    |...|:.     .|...|:.|..:....|::: |||..
  Fly   466 RAKDVYPVRDFRDFVFPVMWLEE----GISELTPAIKRWIYLGTVIAPSAVPIGSYLMI-LGGAF 525

Mouse   456 LLV 458
            .::
  Fly   526 AII 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scarb1	NP_001192012.1	CD36	26..447	CDD:279474	126/436 (29%)
dsb	NP_001097477.1	CD36	103..532	CDD:279474	129/438 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838300
Domainoid	1	1.000	255	1.000	Domainoid score	I2030
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0000618
OrthoInspector	1	1.000	-	-		mtm8809
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.860