Protein Alignment Rnf43 and gol

DIOPT Version :9

• Sequence 1: NP_766036.2
• Gene: Rnf43 / 207742
• MGIID: 2442609
• Length: 784
• Species: Mus musculus
• Sequence 2: NP_001163300.1
• Gene: gol / 38006
• FlyBaseID: FBgn0004919
• Length: 601
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 121/548 - (22%)
• Similarity: 199/548 - (36%)
• Gaps: 130/548 - (23%)

Mouse    71 GVAEVTPAEGKLMQSHPLYLCNASDDDNLEPGFISIVKLESPRRAPRP-----CLSLASKARMAG 130
            |..:|....|:|:  |.....|.|||....|      .:.....||.|     .::|..:.|...
  Fly    96 GEGKVLNVTGRLI--HITATDNFSDDYACTP------YIRGTLGAPIPDKGETWIALVRRGRCTF 152

Mouse   131 ERGA------NAVLFDITEDRSAAE-QLQQPLGLTKPVVLI-----WGSDAAKLMEFVYK----- 178
            |...      ||....|..|:...: :..|..|.|:.:..:     .|.|.:..::..|.
  Fly   153 EEKVKHVYQQNAAGVIIYNDKQVMQLEKMQIKGKTRNIAAVITYQNIGQDLSLTLDKGYNVTISI 217

Mouse   179 -------------NRKAYVWIELKEPPAGANYDVWILLTVVGTVFVIILASVLRIR---CRPHHS 227
                         ||.:.:::.:.          :|:|.::..|: :|...:.|.|   .:...|
  Fly   218 IEGRRGVRTISSLNRTSVLFVSIS----------FIVLMIISLVW-LIFYYIQRFRYMQAKDQQS 271

Mouse   228 RPDPLQQRTARAISQLATRRYQAGCRRARAEWPDSGSSCSSTPVCAICLEEFSEGQELRVISCLH 292
            |  .|...|.:||.::.|:..:.      ::..|..|.|     ||||:|.:.....:|::.|.|
  Fly   272 R--NLCSVTKKAIMKIPTKTGKF------SDEKDLDSDC-----CAICIEAYKPTDTIRILPCKH 323

Mouse   293 EFHRTCVDPWLYQHRTCPLCMFNIVE--GDSFSQAPAASPSYQ-EPGRRLHLIRQHPGHAHYHLP 354
            |||:.|:||||.:|||||:|..::::  |..|..:..:...|| :|.:.|.|:......|.
  Fly   324 EFHKNCIDPWLIEHRTCPMCKLDVLKFYGYVFLGSEESILEYQPDPPQGLALVEARDESAD---- 384

Mouse   355 SAYLLGPSRTSVARTPRPRPFLPSQEPSMGSRHQRLPRTSHLRAPEEQQH----------LAVSP 409
                |..||..|  ...||.|:......:|:|....|    .|.||..|.          :::..
  Fly   385 ----LNRSRDFV--VDFPRVFVLDSGCVVGAREMLFP----CRIPERSQSSLSLRQARDWVSLMS 439

Mouse   410 HPYAQGWGLNRLRCTSQHPAACPVALRRARPHESSGSGESYCTERSGYLADGPASDSSSGPCHGS 474
            :...:..||..:|........  ::.|.:..|..|.|            |||..|....|   |.
  Fly   440 NKLEEQQGLRSMRNDEMQQQL--LSARESARHRRSRS------------ADGRYSTGCFG---GR 487

Mouse   475 SSDSVVNCTDVSLQGIHGSSSTFRSSLSSDFDPLVYCSPEGDLQGKGIQPS----VTSRPR---- 531
            .....|..:.:....:|...:..:.|.||  ..|.:.:.....|.:..|..    ..:|.|
  Fly   488 QRQPSVLVSSLGQPQLHSEVAQMQRSNSS--QALKHLTDAAHAQSRQRQRESFDFARTRRRFMRR 550

Mouse   532 -----SLDSVVPRGETQVSSHIHYHRHR 554
                 ||.|:..||.|. ::|...||.|
  Fly   551 ESDEISLRSLPRRGATS-AAHRQLHRER 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnf43	NP_766036.2	zf-RING_2	270..312	CDD:290367	21/41 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..407		11/52 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	459..478		6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	516..671		14/52 (27%)
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	26/128 (20%)
		UPF0233	226..>258	CDD:299753	6/42 (14%)
		zf-RING_2	301..344	CDD:290367	22/47 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920