DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rnf43 and hrd1

DIOPT Version :9

Sequence 1:NP_766036.2 Gene:Rnf43 / 207742 MGIID:2442609 Length:784 Species:Mus musculus
Sequence 2:NP_596376.1 Gene:hrd1 / 2539900 PomBaseID:SPBC17D11.02c Length:677 Species:Schizosaccharomyces pombe


Alignment Length:458 Identity:94/458 - (20%)
Similarity:155/458 - (33%) Gaps:136/458 - (29%)


- Green bases have known domain annotations that are detailed below.


Mouse   168 DAAKLMEFVYKNRKA-YVWIELKEPPAGANYDVWILLTVVGTVFVIILASVLRIRCRPHHSRPDP 231
            :|:||..::|:.|.. .||.|      .:.|  ...|.|......::..|:|.:...|:.|.|  
pombe   188 EASKLCIYLYEARHLDQVWDE------KSTY--LFRLEVCRDGLRLLAYSLLFMYQFPYVSVP-- 242

Mouse   232 LQQRTARAISQLAT------------RRYQAGCRRARAEWPDSGSS--CSSTPVCAICLEE---- 278
                 ..:|.|:.|            .|::...|...|.:|.:...  .:|...|.||.||    
pombe   243 -----IYSIRQMYTCFYSLFRRIREHARFRQATRDMNAMYPTATEEQLTNSDRTCTICREEMFHP 302

Mouse   279 ------------FSEGQEL--RVISCLHEFHRTCVDPWLYQHRTCPLCMFNIVEGDSFSQAPAAS 329
                        ...|.::  :.:.|.|..|..|:..||.:.:|||:|..:::...|......||
pombe   303 DHPPENTDEMEPLPRGLDMTPKRLPCGHILHFHCLRNWLERQQTCPICRRSVIGNQSSPTGIPAS 367

Mouse   330 PSYQEPGRRLHLIRQHPGHAHYHLPSAYLLGPSRTSVARTPRPRPF--LPSQEPSMGSRHQR--- 389
            |:.    |...:..|.|...:....:| :.|.:.:|....|:...|  :|:...|..:.|.:   
pombe   368 PNV----RATQIATQVPNPQNTPTTTA-VPGITNSSNQGDPQASTFNGVPNANSSGFAAHTQDLS 427

Mouse   390 --LPRTSHLRAPEEQQHLAVSPHPYAQGW------GLNRLRCTSQ-----HPAACPVALRRARPH 441
              :||...||                .||      |..|:...||     :|:|.|.        
pombe   428 SVIPRRIALR----------------DGWTMLPIPGTRRIPTYSQSTSTTNPSATPT-------- 468

Mouse   442 ESSGSGESYCTERSGYLADGPASDSSSGPCHGSSSDSVVNCTDVSLQGIHG---------SSSTF 497
                :|:             |::.:..||....:|.:..|..    :||.|         ||:|.
pombe   469 ----TGD-------------PSNSTYGGPQTFPNSGNNPNFN----RGIAGIVPPGWRLVSSNTQ 512

Mouse   498 RSSLSSDFDPLVYCSPEGDLQGKGIQPSVTSRPRSL------DSVVPRGETQVSSHIHYHRHRHH 556
            ..|.:|....|...:...|.......|:|....|.|      .:..|...:.:||.:     |..
pombe   513 SLSTNSAMTSLYQNASSADNNLGSSLPNVVPLSRGLTQSNETSNTFPAASSNISSQL-----REL 572

Mouse   557 HYK 559
            |.|
pombe   573 HTK 575

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rnf43NP_766036.2 zf-RING_2 270..312 CDD:290367 15/59 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 364..407 10/49 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 459..478 4/18 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 516..671 11/50 (22%)
hrd1NP_596376.1 HRD1 1..514 CDD:227568 80/390 (21%)
zf-RING_2 291..351 CDD:290367 15/59 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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