DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf43 and LOC100536511

DIOPT Version :9

Sequence 1:	NP_766036.2	Gene:	Rnf43 / 207742	MGIID:	2442609	Length:	784	Species:	Mus musculus
Sequence 2:	XP_021329973.1	Gene:	LOC100536511 / 100536511	-ID:	-	Length:	400	Species:	Danio rerio

Alignment Length:	277	Identity:	68/277 - (24%)
Similarity:	119/277 - (42%)	Gaps:	59/277 - (21%)

- Green bases have known domain annotations that are detailed below.

Mouse    82 LMQSHPLYLC--NASDDDNLEPGFISIVKLESPRRAPRPCLSLASKARMAGERGANAVLFDITED 144
            |..|.|| .|  |.:...:.:| :|:::|...       | |...|...|...||:||:. ..||
Zfish    82 LPNSDPL-ACSKNTTFTASHQP-WIALIKTGK-------C-SYTKKINAAQREGASAVVI-YNED 135

Mouse   145 RSAAEQLQQPLGLTKPVVLIWGSDAAKLMEF----VYKNRKAYV---WIELK-----EPPAGANY 197
                       |....|:|:..|.|..|:..    :...:.||:   .:::.     ..|.|...
Zfish   136 -----------GTGNDVILMMYSGADDLVAINIGNILGTQIAYLINNGLDVNMTINVATPTGVWK 189

Mouse   198 DVW---ILLTVVG----TVFVIILASVLRIRCRPHHSRPD-PLQQRTARAISQLATRRYQAGCRR 254
            ..|   :..|.:|    |:|......:.|:.......|.. .:::.|.:||.:|..|..:.....
Zfish   190 GTWAYVLSFTFIGITAVTMFYFAFLFMKRMYINRQLRRQQMEIKRETEKAIGKLEVRTLRTNDPE 254

Mouse   255 ARAEWPDSGSSCSSTPVCAICLEEFSEGQELRVISCLHEFHRTCVDPWLYQHRTCPLCMFNI--- 316
            ..::  |:|        |.:|.:.:..|:::.|:.|.|.:|:.|::|||.:|.|||:|.:||
Zfish   255 VDSD--DTG--------CVVCTDSYQRGEQVTVLPCRHLYHKKCIEPWLLEHPTCPMCKYNILKS 309

Mouse   317 -VEGDSFSQ-APAASPS 331
             :|.||:.| :|::|.|
Zfish   310 SIEEDSYDQPSPSSSSS 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf43	NP_766036.2	zf-RING_2	270..312	CDD:290367	15/41 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..407
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	459..478
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	516..671
LOC100536511	XP_021329973.1	PA_GRAIL_like	47..179	CDD:239037	27/118 (23%)
		zf-rbx1	<188..303	CDD:331150	29/124 (23%)
		RING_Ubox	262..308	CDD:327409	18/45 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920