DRSC/TRiP Functional Genomics Resources

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Protein Alignment Serpinb8 and nec

DIOPT Version :9

Sequence 1:NP_035589.1 Gene:Serpinb8 / 20725 MGIID:894657 Length:374 Species:Mus musculus
Sequence 2:NP_524851.1 Gene:nec / 45908 FlyBaseID:FBgn0002930 Length:476 Species:Drosophila melanogaster


Alignment Length:380 Identity:110/380 - (28%)
Similarity:177/380 - (46%) Gaps:34/380 - (8%)


- Green bases have known domain annotations that are detailed below.


Mouse    11 FAISLLKILSEKDKSRNLFFCPMSVSSALAMVYLGAKGNTATQMSEVLGLSGNG-DVHQSFQTLL 74
            |:..|.|.:.:....:|:.|.|.||.:.||::|..:.|.|..::.:....|.|. .|.|.|::::
  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESVI 174

Mouse    75 AEINKTDTQYLLKSACRLFGEESCDFLSTFKESCHKFYQAGLE--ELSFAKDTEGCRKHINDWVS 137
            ......:...|..:....:..|......::.|....::.||.|  ::..||||..   .||.||.
  Fly   175 KYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAA---KINAWVM 236

Mouse   138 EKTEGKISEVLSPGTVCPLTKLVLVNAMYFKGKWKAQFDRKYTRGMPFK-TNQEKKTVQMMFKHA 201
            :.|..||.::::|..|.|.|:.:||||:||:|:|:.:|....|....|: ||.....|.|||...
  Fly   237 DTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDD 301

Mouse   202 KFKMGHVDEVNMQVLALPYAEEELSMVILLPDESTDLAVVEKALTYEKLRAWTNPE--------T 258
            .:.:..:.|:....|.|.|.:...||:||||:|:|.|.        :.|:..:.||        .
  Fly   302 VYGLAELPELGATALELAYKDSATSMLILLPNETTGLG--------KMLQQLSRPEFDLNRVAHR 358

Mouse   259 LTESQVQVFLPRLKLEESYDLETVLQNLGMTDAFEETRADFSGMTTK---KNVPVSKVAHKCFVE 320
            |....|.|.||:.:.|...|:...|:|||:...|..     :...||   :.|.|||:..|.::.
  Fly   359 LRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTP-----NSQVTKLMDQPVRVSKILQKAYIN 418

Mouse   321 VNEEGTEAAAATAVIRNARCCRTEP-RFCADHPFLFFIWHHKTSSILFCGRFSSP 374
            |.|.||||:||:...........:| .|.|:.||:|.:  ...:|:||.|....|
  Fly   419 VGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAV--RTPASVLFIGHVEYP 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Serpinb8NP_035589.1 SERPIN 4..374 CDD:294093 109/378 (29%)
necNP_524851.1 SERPIN 108..468 CDD:238101 109/375 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.930

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