DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Serpinb9 and nec

DIOPT Version :9

Sequence 1:	NP_033282.1	Gene:	Serpinb9 / 20723	MGIID:	106603	Length:	374	Species:	Mus musculus
Sequence 2:	NP_524851.1	Gene:	nec / 45908	FlyBaseID:	FBgn0002930	Length:	476	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	106/369 - (28%)
Similarity:	179/369 - (48%)	Gaps:	12/369 - (3%)

- Green bases have known domain annotations that are detailed below.

Mouse    11 FAIHLLKMLCQSNPSKNVCYSPASISSALAMVLLGAKGQTAVQISQALGLNKEE-GIHQGFQLLL 74
            |:..|.|.:.:|...:||.:||.|:.:.||::...:.|:|..::.:|...:|.. .:.|.|:.::
  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESVI 174

Mouse    75 RKLNKPDRKYSLRVANRLFADKTCEVLQTFKESSLHFYDSEMEQLSFAEEAEVSRQHINTWVSKQ 139
             |..|......|.:|.:::.::....:....:....||.|...:....:.|:.:...||.||...
  Fly   175 -KYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAKINAWVMDT 238

Mouse   140 TEGKIPELLSGGSVDSETRLVLINALYFKGKWHQPFNKEYTMDMPFKINKDEKRPVQMMCREDTY 204
            |..||.:|::...||.:|:.:|:||:||:|:|...|....|....|:........|.||..:|.|
  Fly   239 TRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDDVY 303

Mouse   205 NLAYVKEVQAQVLVMPYEGMELSLVVLLPDEGVDLSKVENNLTFEKLTAWMEADFMKSTDVEVFL 269
            .||.:.|:.|..|.:.|:....|:::|||:|...|.|:...|:..:......|..::...|.|.|
  Fly   304 GLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEFDLNRVAHRLRRQSVAVRL 368

Mouse   270 PKFKLQEDYDMESLFQRLGVVDVFQEDKADLSGM-SPERNLCVSKFVHQSVVEINEEGTEAAAAS 333
            |||:.:.:.||....:.|||..:|..:......| .|.|   |||.:.::.:.:.|.||||:|||
  Fly   369 PKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMDQPVR---VSKILQKAYINVGEAGTEASAAS 430

Mouse   334 AIIEFCCASSVP---TFCADHPFLFFIRHNKANSILFCGRFSSP 374
             ..:|...|..|   .|.|:.||:|.:|  ...|:||.|....|
  Fly   431 -YAKFVPLSLPPKPTEFVANRPFVFAVR--TPASVLFIGHVEYP 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Serpinb9	NP_033282.1	serpin	1..374	CDD:393296	105/367 (29%)
nec	NP_524851.1	SERPIN	108..468	CDD:238101	105/364 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930