DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Serpinb9c and Spn88Eb

DIOPT Version :9

Sequence 1:	XP_006516681.1	Gene:	Serpinb9c / 20707	MGIID:	894669	Length:	403	Species:	Mus musculus
Sequence 2:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster

Alignment Length:	412	Identity:	114/412 - (27%)
Similarity:	189/412 - (45%)	Gaps:	46/412 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse    24 EPPFLN---IVYEANGTFAVNLLRMLCNNNPSKNVCYSPINISSALAMFLLGVKGNTEIQISEAI 85
            |..|||   .:::....|::.|::.:....||.|:.:||.:..:||.:........||.::::|:
  Fly    24 ELSFLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQAL 88

Mouse    86 GLNTAIDIHQSFLWILNILKKPTRKYTFR---------MANRLFAENTCEFLPTFKEPCLQFYHW 141
            .|..|::..|    :|.......|:..||         .|||:|.:.|......|.    ...:.
  Fly    89 NLGWALNKQQ----VLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFN----TLLYG 145

Mouse   142 EMEHLPFTKAPEEARNHINTWVCKNTKGKIPELLSSGSVDSETRLVLVNALYFKGRWHHQFDIKS 206
            ..:.|.|...||.....||.|:...|..:|.::|||..:...|.|||.||.|.||:|..||.::.
  Fly   146 ATKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEE 210

Mouse   207 TRKMPFKINKDEERPVQMMFQEDMFKLAYVNEVQVQVLVLP----YKGKE-----------LSLV 256
            |...||.||:.|:..|.||.:...||:.....:|.|::.||    ||.||           :|::
  Fly   211 TALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMI 275

Mouse   257 VLLPDDG-VELSKVEGNLTFEKLSAWTK---PDYLKTTKVLVFLPKFKLEDYYDMESIFQDLGVG 317
            ::||:.. :.|::|...|..:.:..|.:   |.     |:.:.||||:.|...::..|...:||.
  Fly   276 IILPNSNKISLNRVISRLNADSVKKWFERALPQ-----KIELSLPKFQFEQRLELTPILSLMGVN 335

Mouse   318 DIFQGGKADLSEMSPER-GLCVSKFIQKCVVEVNEEGTEATAATADDTVCSAETHDGQTFCADHP 381
            .:|. ..|...:::.:. .|.:........::|:|.|:.|.|||......|:...|...|..:||
  Fly   336 TMFT-RNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHP 399

Mouse   382 FLFFIRHNKTNSILFCGRFSFP 403
            |:|.|...|.::|||.|.:|.|
  Fly   400 FVFLIYDEKVDTILFAGVYSDP 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Serpinb9c	XP_006516681.1	serpin	28..403	CDD:393296	111/406 (27%)
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	108/394 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820