Protein Alignment Serpina1e and Spn42Dd

DIOPT Version :10

• Sequence 1: NP_033273.1
• Gene: Serpina1e / 20704
• MGIID: 891967
• Length: 413
• Species: Mus musculus
• Sequence 2: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 365
• Identity: 100/365 - (27%)
• Similarity: 175/365 - (47%)
• Gaps: 27/365 - (7%)

Mouse    58 ELVHQSNTS-NIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHNSFQHLLQTL 121
            :|:.:|:|: |:..|||||.|..:|:.:|::|.|..::...|  .|....:..:...:..||..|
  Fly    23 QLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL--GLPSEDKEAVAARYGALLNDL 85

Mouse   122 NRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGK 186
            ...:....|...|.::||:...|.:.:....:..:::|..|::......|.:.||.:|...|.||
  Fly    86 QGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTSGK 150

Mouse   187 IVEAVK--KLEQDTVFVLANYILFKGKWKKPFDPENTKQAEFHVDESTTVKVPMMTLSGMLDVHH 249
            |...:.  .:..|...:|.|.|.|||:|:..|||..|:.:.|.|..:.:|.|.||...|....::
  Fly   151 IKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANY 215

Mouse   250 CSTLSSWVLLMDYA-GNATAVFLLPDDGK-MQHLEQTL---NKELISKFLLNRRRRLAQIHIPRL 309
            ...|.:.|:.:.|. .|.:....||.:.: :..||:.:   .:.|::|.:        .:.:|:.
  Fly   216 FRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEKIVGFARPLVAKEV--------YLKLPKF 272

Mouse   310 SISGNYNLETLMSPLGITRIFNSGADLSGITEENAPLKLSQAVHKAVLTIDETGTEAAAATVL-- 372
            .|.....|:..:..|||..:|...:||||:..:.:..|:||..|||.|.::|.|.|||.||.:
  Fly   273 KIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAV 337

Mouse   373 --QGGFLSMPPILHFNRPFLFIIFEEHSQSPLFVGKVVDP 410
              :.||.:   .|..:.||.|:|  ..:.:..|.|:||.|
  Fly   338 TNRAGFST---FLMADHPFAFVI--RDANTIYFQGRVVSP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Serpina1e	NP_033273.1	serpinA1_A1AT	44..412	CDD:381012	100/365 (27%)
		RCL	368..387		5/22 (23%)
Spn42Dd	NP_001163067.1	serpin42Dd-like_insects	12..372	CDD:381070	99/363 (27%)