Protein Alignment Serpina1b and Spn42Dd

DIOPT Version :10

• Sequence 1: NP_033270.3
• Gene: Serpina1b / 20701
• MGIID: 891970
• Length: 413
• Species: Mus musculus
• Sequence 2: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 362
• Identity: 104/362 - (28%)
• Similarity: 172/362 - (47%)
• Gaps: 21/362 - (5%)

Mouse    58 ELVHQSNTS-NIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHKSFQHLLQTL 121
            :|:.:|:|: |:..|||||.|..:|:.:|::|.|..::...|  .|....:..:...:..||..|
  Fly    23 QLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL--GLPSEDKEAVAARYGALLNDL 85

Mouse   122 NRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGK 186
            ...:....|...|.::||:...|.:.:....:..:::|..|::......|.:.||.:|...|.||
  Fly    86 QGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTSGK 150

Mouse   187 IVEAVK--ELDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDKSTTVKVPMMMLSGMLDVHH 249
            |...:.  .:..|....|.|.|.|||:|:..|||..|..:.|.|..:.:|.|.||...|....::
  Fly   151 IKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANY 215

Mouse   250 CSILSSWVLLMDYA-GNASAVFLLPEDGK-MQHLEQTL---NKELISKILLNRRRRLVQIHIPRL 309
            ...|.:.|:.:.|. .|.|....||.:.: :..||:.:   .:.|::|        .|.:.:|:.
  Fly   216 FRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEKIVGFARPLVAK--------EVYLKLPKF 272

Mouse   310 SISGDYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSKAVHKAVLTIDETGTEAAAAT-VFE 373
            .|.....||..:..|||..:|.:.:||||:..:.:..|:|:..|||.|.::|.|.|||.|| |..
  Fly   273 KIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAV 337

Mouse   374 AVPMSMPPILRFDHPFLFIIFEEHTQSPIFVGKVVDP 410
            .........|..||||.|:|.:.:|  ..|.|:||.|
  Fly   338 TNRAGFSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Serpina1b	NP_033270.3	serpinA1_A1AT	44..412	CDD:381012	104/362 (29%)
		RCL	368..387		4/19 (21%)
Spn42Dd	NP_001163067.1	serpin42Dd-like_insects	12..372	CDD:381070	103/360 (29%)