Protein Alignment Sox17 and Sox100B

DIOPT Version :9

• Sequence 1: NP_001276393.1
• Gene: Sox17 / 20671
• MGIID: 107543
• Length: 419
• Species: Mus musculus
• Sequence 2: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 135/516 - (26%)
• Similarity: 182/516 - (35%)
• Gaps: 160/516 - (31%)

Mouse     1 MSSPDAGYASDDQSQP---------------RSAQ------------PAVMAGLGPCPWAESLSP 38
            ||...:...|.|:::|               :.||            .|||..|....|
  Fly     1 MSDSSSSNCSKDRAKPVETLVLANYALKAEQKKAQGQGGRKEDERITTAVMKVLEGYDW------ 59

Mouse    39 LGDVKVKGEVVASSGAPAGTSGRAKAESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLG 103
                   ..|.||:.||..     :.:..|:||||||||||:..|:.:::|.|.|.|:||||.||
  Fly    60 -------NLVQASAKAPTD-----RKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLG 112

Mouse   104 KSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRMKRVEGGFLHALVEPQAGALG 168
            |.||.|..::|:||:|.||:||:.|.|:||:|||:|||:|            ...|...|:|
  Fly   113 KLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKK------------ARVLPSQQSG--- 162

Mouse   169 PEGGRVAMDGLGLPFPEPGYPA-----GPPLMSPHMGPHYRDCQGLGAPALDGYPLPTPDTSPLD 228
             |||.        |.||....|     |.|..|...|...   .|.|..|.|.....:..:....
  Fly   163 -EGGS--------PGPEMTLSATMGSSGKPRSSNSNGQRR---AGKGNAAADLGSCASTISHANV 215

Mouse   229 GVEQDPAF----FAAPLPGDCPAA---------GTYTYAPVSDYAVSVEPPAGPMRVGPDPSGPA 280
            |......|    |...|...|.|:         |..:....:....|:.|||.|..|.|..
  Fly   216 GSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVAPSN---- 276

Mouse   281 MPGILAPPSALH---LYYGAMGSPAASAGRGFHAQPQQ--------PLQPQAPPPPPQQQHPAHG 334
                 |..||.:   |....:..|.|:||.|:....:.        .:..|......|......|
  Fly   277 -----AKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGG 336

Mouse   335 PGQP------------------SPPPEALPCRDG---TESNQPTELL------------GEVDRT 366
            .||.                  |.|..:.|...|   ||..|..:.|            .::|..
  Fly   337 AGQEMDFLENINGYGGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEALNYKPAAADIDPK 401

Mouse   367 EFEQY-----LPFVYKPEMGLPYQGHDCGVNLS-----DSHGAISSVVSDASS----AVYY 413
            |.:||     ||......   |:..|.....|.     :|..::||..|.|||    |.||
  Fly   402 EIDQYFMDQMLPMTQHHH---PHHTHPLHHPLHHSPPLNSSASLSSACSSASSQQPVAEYY 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox17	NP_001276393.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		10/52 (19%)
		SOX-TCF_HMG-box	67..138	CDD:238684	40/70 (57%)
		Sox17_18_mid	203..253	CDD:403331	11/62 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..356		15/81 (19%)
Sox100B	NP_651839.1	SOX-TCF_HMG-box	76..146	CDD:238684	39/69 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810