Protein Alignment Sox13 and cic

DIOPT Version :10

• Sequence 1: XP_011246247.1
• Gene: Sox13 / 20668
• MGIID: 98361
• Length: 621
• Species: Mus musculus
• Sequence 2: NP_001262755.1
• Gene: cic / 53560
• FlyBaseID: FBgn0262582
• Length: 2150
• Species: Drosophila melanogaster
• Alignment Length: 754
• Identity: 150/754 - (19%)
• Similarity: 270/754 - (35%)
• Gaps: 236/754 - (31%)

Mouse    16 DSASTMVNCTIKSEEKKEPCHEAP---QGAAP--AVETQPGDPA----------LASQDATNAKA 65
            |:|:.:|  ::.|.....|.:.:|   .||:|  |:...|.:.:          :|:|.....:.
  Fly   755 DAAAMLV--SLSSSRSATPSYTSPVNHAGASPLNAIAHSPVNVSATHRQNFFTPIANQSQQQQQQ 817

Mouse    66 PPQDCASPESS---GSPEPKRPAASEAASGSQERLDFNRNLQEVVPAIEKLLSSDWKERFLG-RS 126
            .|  .|.|..|   .:|.|....|:..:|.:......|.|            :|:|:   :| .|
  Fly   818 QP--VAVPLDSKWKTTPSPVLYNANNNSSNNNTSSSNNNN------------NSNWE---VGSNS 865

Mouse   127 NVEAKDVKAFLCGTGTQESLAEKELQLLVMIH----QLSALRDQ--------------------- 166
            |.......|.....|.| .|..:...:.:::|    |...|:.|
  Fly   866 NTHVAATAAATSTVGAQ-PLPPQTTPVSLVMHAPPPQQQPLQQQHHHHQPPPPPPASLPAPSAPP 929

Mouse   167 ---LLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYV 228
               ..::|:...:..:::                :|:..|||  .||      |||.||...|:|
  Fly   930 TSGSSSSHNSVGHATSVI----------------RISSSQQQ--HQQ------QQQHQQQAHPHV 970

Mouse   229 MIPAFPPSHQPLPVTPD-SQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRSGVA--------AHH 284
            ::......|   ||..| :||::|:.|....        .|.|..|....:.||        |.:
  Fly   971 VVSGGQTFH---PVIVDATQLSVPLPPTTVS--------FHQPNTPTSTAASVASMSQDKMLAKN 1024

Mouse   285 PLQEP-----PQ--PLN-LTAKPKVPELPNTSSSPSLKMNSCGPRPASH-----GAPTRDLQSSP 336
            ....|     |.  |:: .:..|..|.|..::||.::.|..   :...|     ....:..|.||
  Fly  1025 GYNAPWFKLLPHMTPMSKASPAPVTPTLTTSASSYNVVMMQ---QQQQHQQLQQQQQLQQQQQSP 1086

Mouse   337 PSLPLG-----------FLGEGDAVTKAIQDARQLLHSHSGALEN--------SPNTPFRKDL-- 380
            |.:||.           ....|..:..::.||:....:.:.|:.|        .|:.....|:
  Fly  1087 PQMPLNHNNNHLIVSAPLSSPGKPLNCSMNDAKVAAAAAAAAVANQRQKQQQEEPDDQLDDDVFE 1151

Mouse   381 -----ISLDS--SPAKERL--EESCVHPLEEAMLSCDMDG---------SRHFSESRN------- 420
                 ||.:|  ..|..||  ..|.:..|||    |..||         ::..|:|.:
  Fly  1152 TTTPGISANSKKQTAAMRLPTHNSNIRKLEE----CHDDGAAGAPATSAAKRRSQSLSALQQQQQ 1212

Mouse   421 ----------------SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQE 469
                            :..|:|||||||:::|..|:.:.:..|:..|.::|||||..|.::..::
  Fly  1213 QQQQAGAAGTAAGQPANKKIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQ 1277

Mouse   470 KQPYYEEQARLSRQHLEKYPDYKYKPRPKR-----TCVVEGR---RLRVGEYKALMRTRRQGARQ 526
            |..|:|..:.:...|.:.:|::|:..:.:|     |....|:   ....|:.|..:.:.......
  Fly  1278 KAQYHELASSVKDAHFKLHPEWKWCSKDRRKSSTSTATPGGKASGAAGTGDAKQRLVSVDGSDSL 1342

Mouse   527 SYTIPP-------QAGQAQVSSDILFPRAAGLPLARPLVEHYDPQGLDPNMPVIINTC------- 577
            .:.:.|       ..|...:|||:   :...:||.   :::|:            :||
  Fly  1343 EHDMCPSTPGGSGSCGGQGISSDL---QGDIIPLT---IDNYN------------STCDEAPTTI 1389

Mouse   578 SLREEGEG---TDDRHSVADGEMYRYSEDEDSEGDEKSD 613
            |::..|.|   .::..|..|.:|....|::..:..:|.|
  Fly  1390 SMKGNGNGKLMKNELPSDEDEQMLVVEEEQQQQTVKKID 1428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox13	XP_011246247.1	HMG-box_SoxD	423..499	CDD:438839	24/75 (32%)
cic	NP_001262755.1	DUF4819	349..432	CDD:465014
		HMG-box_CIC-like	1231..1308	CDD:438806	24/76 (32%)