Protein Alignment Sox1 and Sox100B

DIOPT Version :9

• Sequence 1: NP_033259.2
• Gene: Sox1 / 20664
• MGIID: 98357
• Length: 391
• Species: Mus musculus
• Sequence 2: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 506
• Identity: 115/506 - (22%)
• Similarity: 168/506 - (33%)
• Gaps: 230/506 - (45%)

Mouse    44 TKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLR 108
            |...::.:||||||||||::..||.|:::.|.:.|||:||.||..||.:.:::|:||::.|::||
  Fly    70 TDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLR 134

Mouse   109 ALHMKEHPDYKYRPRRKTKTLLKKD----------KYSLAGGLLAAG------------AGGGGA 151
            ..|.:|||||||:||||...:|...          :.:|:..:.::|            ||.|.|
  Fly   135 MTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRAGKGNA 199

Mouse   152 AVAMG------------------------------------------------------------ 156
            |..:|
  Fly   200 AADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLT 264

Mouse   157 ----------------------------------VGVGVGA--------AAVGQ---RLESPG-- 174
                                              .|.|.|.        .|:|:   :.:|.|
  Fly   265 PPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQ 329

Mouse   175 -GAAGGG-------YAHVNGWANGAYPGSVAAAAA----------AAAMMQEAQL-----AYGQH 216
             ||.|||       ..::||:  |.|.||..:..|          |....|:.|.     |....
  Fly   330 SGAEGGGAGQEMDFLENINGY--GGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEALNYK 392

Mouse   217 PGAGGAHP----------------HAHPAHPHP-HHPHAHPHNPQPMHRYDMGALQYSPISNSQG 264
            |.|....|                |.||.|.|| |||                 |.:||..||..
  Fly   393 PAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHHP-----------------LHHSPPLNSSA 440

Mouse   265 YMSASPSGYGGIPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAP 329
            .:|:           |.::|::....|.....:..:.||::||            ..|:..|..|
  Fly   441 SLSS-----------ACSSASSQQPVAEYYEHLGYSPAASSAS------------QNPNFGPQQP 482

Mouse   330 ----AHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLP-QHY 375
                |.|..|..||         ||     |.....:..|.:.|..| ||:
  Fly   483 YANGAASMTPTLGD---------PA-----PQQELQSQQQEQQHQNPSQHH 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox1	NP_033259.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		1/7 (14%)
		SOX-TCF_HMG-box	50..121	CDD:238684	36/70 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..249		12/51 (24%)
Sox100B	NP_651839.1	SOX-TCF_HMG-box	76..146	CDD:238684	35/69 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810