Protein Alignment EPS8 and CG8907

DIOPT Version :10

• Sequence 1: XP_047284450.1
• Gene: EPS8 / 2059
• HGNCID: 3420
• Length: 842
• Species: Homo sapiens
• Sequence 2: NP_001247146.1
• Gene: CG8907 / 42050
• FlyBaseID: FBgn0038466
• Length: 732
• Species: Drosophila melanogaster
• Alignment Length: 324
• Identity: 63/324 - (19%)
• Similarity: 112/324 - (34%)
• Gaps: 85/324 - (26%)

Human    65 LNH-THPSACQGQRLFEKLLQLTSQNIEIKLVSDVTADSKVLEAL--------KLKGAEVTYMNM 120
            ||| .||.  :||.|..:..::.|:..:.|:.|.:| |.|:.:..        |....:||:.:.
  Fly    32 LNHGMHPR--EGQFLICEESEIESKVFDNKIFSYIT-DLKIQDPQPSDFVTFPKNVHEKVTFKSW 93

Human   121 TAYNKGRLQSSF--------W--IVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRI 175
            ..::......:|        |  :||...:.|..||:    .|.|..:..:.|.     |..|.:
  Fly    94 IGFSSVPHHLTFNRKVAYADWYGLVDSSGIEIKFAGV----FGVMIAVNDLDYE-----LTGQHL 149

Human   176 FALYS---SLKFKSRVPQTWSKRL-YGVYDNE--KKLQLQLNETKSQA-------------FVSN 221
            |.:..   .||..:...:.|.|.| :....|:  ||.|.:::....||             .:||
  Fly   150 FKVVQRPWKLKSTADTSEFWQKLLQFEEKSNKQVKKPQCEISMENRQAGNNEMTSPEPTYKELSN 214

Human   222 SPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVR 286
            :.||...:|.:..                         :|..|::..:..|.|:.........:.
  Fly   215 TVKLLQQENINLK-------------------------NSVQTRKDQFSQLYAQKERYESTNEIE 254

Human   287 VRLLLSFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNK 350
            :..|....:|...|....|:....:.||    .:.||      .|..|.:.:...:..:||..|
  Fly   255 INRLKKCVEEEIELNRQLIAENTRLATE----QVSVK------RNMEAARSELQRSEEKLNNAK 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EPS8	XP_047284450.1	PTB_EPS8	84..211	CDD:269921	31/150 (21%)
		SH3_Eps8	555..608	CDD:212698
		SAM_EPS8-like	740..804	CDD:188939
CG8907	NP_001247146.1	PTB_EPS8	43..175	CDD:269921	28/141 (20%)
		SH3_Eps8	439..492	CDD:212698
		SAM_3	630..693	CDD:436214