Protein Alignment EPS8 and Eps8

DIOPT Version :10

• Sequence 1: XP_047284450.1
• Gene: EPS8 / 2059
• HGNCID: 3420
• Length: 842
• Species: Homo sapiens
• Sequence 2: NP_001258516.1
• Gene: Eps8 / 13860
• MGIID: 104684
• Length: 847
• Species: Mus musculus
• Alignment Length: 826
• Identity: 733/826 - (88%)
• Similarity: 782/826 - (94%)
• Gaps: 1/826 - (0%)

Human    17 VKDTMNGHISNHPSSFGMYPSQMNGYGSSPTFSQTDREHGSKTSAKALYEQRKNYARDSVSSVSD 81
            |:..||||:||..|.:|:||||:|||||||.:||.||||.|:|||||||||||||||||||||||
Mouse    23 VRAGMNGHMSNRSSGYGVYPSQLNGYGSSPPYSQMDREHSSRTSAKALYEQRKNYARDSVSSVSD 87

Human    82 ISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELE 146
            :||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||
Mouse    88 VSQYRVEHLTTFVLDRKDAMITVEDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELE 152

Human   147 NFPLNTIQHCQAVMHSCSYDSVLALVCKEPTQNKPDLHLFQCDEVKANLISEDIESAISDSKGGK 211
            |||||||.|||||:|:|||||:||||||||||:||||||||||||||||||||||||||||||||
Mouse   153 NFPLNTISHCQAVVHACSYDSILALVCKEPTQSKPDLHLFQCDEVKANLISEDIESAISDSKGGK 217

Human   212 QKRRPDALRMISNADPSIPPPPRAPAPAPPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYHEQE 276
            |||||:|||||:.|||.||||||||||.|||||||||||||||||||||||||||||||||||||
Mouse   218 QKRRPEALRMIAKADPGIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYHEQE 282

Human   277 ETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKNKKGKRKGPGEGVLTLRAK 341
            ||||||||||||||||||||||||||||||||||||||||||||||:||.|||||||||||||||
Mouse   283 ETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKSKKSKRKGPGEGVLTLRAK 347

Human   342 PPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVVQATGGPELASSVLSPLL 406
            |||||||:|||||||||||||||||||||||||:|||||||||||||||||||||||||||||||
Mouse   348 PPPPDEFVDCFQKFKHGFNLLAKLKSHIQNPSASDLVHFLFTPLNMVVQATGGPELASSVLSPLL 412

Human   407 NKDTIDFLNYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPPYVPRFRNGWEPPMLNFMGATMEQ 471
            .|||:||||||...:||:||||||.:|:|.|||||||||||||||||||||||||||||||..||
Mouse   413 TKDTVDFLNYTATAEERKLWMSLGDSWVKVRAEWPKEQFIPPYVPRFRNGWEPPMLNFMGAPTEQ 477

Human   472 DLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPADGYAFSSNIYTRGSHLDQGEAAVAFKPT 536
            |:||||||||| |||||||:.||||||||:||:|.||||||:||::|.||.|.|.||||:.||.|
Mouse   478 DMYQLAESVAN-AEHQRKQDSKRLSTEHSNVSDYPPADGYAYSSSMYHRGPHADHGEAAMPFKST 541

Human   537 SNRHIDRNYEPLKTQPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVP 601
            .|..:||||:.:||||||||||||||||||:|||||:|||:|||||||:||||||||||||||||
Mouse   542 PNHQVDRNYDAVKTQPKKYAKSKYDFVARNSSELSVMKDDVLEILDDRRQWWKVRNASGDSGFVP 606

Human   602 NNILDIVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVP 666
            ||||||:|.||||:|||||||||||||||.|||.|.||||.||||||||||||||||||.||||.
Mouse   607 NNILDIMRTPESGVGRADPPYTHTIQKQRTEYGLRSADTPSAPSPPPTPAPVPVPLPPSVPAPVS 671

Human   667 VSKVPANITRQNSSSSDSGGSIVRDSQRHKQLPVDRRKSQMEEVQDELIHRLTIGRSAAQKKFHV 731
            |.|||||:||||||||||||||||||||:|||||||||||||||||||..||||||||||:||||
Mouse   672 VPKVPANVTRQNSSSSDSGGSIVRDSQRYKQLPVDRRKSQMEEVQDELFQRLTIGRSAAQRKFHV 736

Human   732 PRQNVPVINITYDSTPEDVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCPEGARVYSQ 796
            ||||||||||||||:||:|||||||||||||||||||||||||||||||||||:||||||||::|
Mouse   737 PRQNVPVINITYDSSPEEVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRSVCPEGARVFNQ 801

Human   797 ITVQKAALEDSSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH 842
            |||||||||||:||||||||||||||||||||||||||||||||||
Mouse   802 ITVQKAALEDSNGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EPS8	XP_047284450.1	PTB_EPS8	84..211	CDD:269921	120/126 (95%)
		SH3_Eps8	555..608	CDD:212698	48/52 (92%)
		SAM_EPS8-like	740..804	CDD:188939	58/63 (92%)
Eps8	NP_001258516.1	PTB_EPS8	90..217	CDD:269921	120/126 (95%)
		SH3_Eps8	560..613	CDD:212698	48/52 (92%)
		SAM_EPS8-like	745..809	CDD:188939	58/63 (92%)