Protein Alignment Smarcb1 and Snr1

DIOPT Version :10

• Sequence 1: NP_035548.1
• Gene: Smarcb1 / 20587
• MGIID: 1328366
• Length: 385
• Species: Mus musculus
• Sequence 2: NP_730935.1
• Gene: Snr1 / 40657
• FlyBaseID: FBgn0011715
• Length: 370
• Species: Drosophila melanogaster
• Alignment Length: 386
• Identity: 254/386 - (65%)
• Similarity: 301/386 - (77%)
• Gaps: 20/386 - (5%)

Mouse     4 MALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIV---A 65
            ||| :|:|.|||.||||:.||:|.:|||||||:|.|||.|||:||.:.|.:.:.||||::.   .
  Fly     1 MAL-QTYGDKPVAFQLEEGGEYYYVGSEVGNYMRHFRGILYKKYPGMTRIVLSNEERKRLAESGL 64

Mouse    66 SSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQ 130
            |||              .||:||:||:|.||::|:.||||||:|||::|......||.|:|:..|
  Fly    65 SSH--------------ILASSVSLLRAVEVDDIMAGNDEKYRAVSVNTSDTPVPRESKSKKQPQ 115

Mouse   131 WVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENASQPEVLVPIRLDMEI 195
            :|||:|||| ||||||.:|.|||||:...|.||||:||||.||....|||:|.|.|||||||||:
  Fly   116 YVPTMPNSS-HLDAVPQATPINRNRVHTKKVRTFPMCFDDTDPTASLENAAQKECLVPIRLDMEL 179

Mouse   196 DGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIRQQIESYPTD-SILEDQSD 259
            :||||||.||||.||.::|||.|:|:||||||||||.||||||.|||||||::|.| .|||:..|
  Fly   180 EGQKLRDTFTWNKNESMITPEQFAEVLCDDLDLNPLPFVPAIAQAIRQQIEAFPNDPPILEETCD 244

Mouse   260 QRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQK 324
            ||||:||||||||.|||||.|||||||.|:||:||:|||:||||||||||.||||||||||||.:
  Fly   245 QRVIVKLNIHVGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGEFVTAIAYSIRGQLSWHCR 309

Mouse   325 TYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW 385
            ||||||.||.|:::..||..|||.|.|.|||||||||||||||||||||||||||||...|
  Fly   310 TYAFSEAPLSTIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRNTRRMRRLANTTTGW 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smarcb1	NP_035548.1	DNA-binding. /evidence=ECO:0000250|UniProtKB:Q12824	1..113		58/111 (52%)
		WH_NTD_SMARCB1	9..107	CDD:411036	50/100 (50%)
		SNF5	181..363	CDD:428158	136/182 (75%)
		2 X approximate tandem repeats	186..319		104/133 (78%)
		MYC-binding. /evidence=ECO:0000250|UniProtKB:Q12824	186..245		46/58 (79%)
		Interaction with PPP1R15A. /evidence=ECO:0000250|UniProtKB:Q12824	304..318		12/13 (92%)
Snr1	NP_730935.1	WH_NTD_SMARCB1	5..92	CDD:411036	50/100 (50%)
		SNF5	165..348	CDD:428158	136/182 (75%)