DRSC/TRiP Functional Genomics Resources

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Protein Alignment Snai2 and esg

DIOPT Version :9

Sequence 1:NP_035545.1 Gene:Snai2 / 20583 MGIID:1096393 Length:269 Species:Mus musculus
Sequence 2:NP_476600.1 Gene:esg / 34903 FlyBaseID:FBgn0001981 Length:470 Species:Drosophila melanogaster


Alignment Length:264 Identity:140/264 - (53%)
Similarity:164/264 - (62%) Gaps:44/264 - (16%)


- Green bases have known domain annotations that are detailed below.


Mouse    17 PNYSELD--THTVIISPYLYESYPIPVIPKPEILTSGAYSPITVWT-SSAAP---LHSPLPSGLS 75
            |.|..|.  |||        ..:..|:.|        |||..:.:: .|..|   ..|.||..||
  Fly   215 PGYPSLGGYTHT--------HHHHAPISP--------AYSENSYYSMRSMTPESSCSSSLPEDLS 263

Mouse    76 PLTGYSSSLGRVSPPPSSDTSSKDHSGSESP-----ISDEEERLQPKLSDPHAIEAEKFQCNLCN 135
             |...:.:|...:..|....::|  :|..||     .|.::::.||          .::||..|.
  Fly   264 -LKHKNLNLNLNTSQPGEQAAAK--TGDMSPETMPNASAKKDKNQP----------PRYQCPDCQ 315

Mouse   136 KTYSTFSGLAKHKQLHCDA----QSRKSFSCKYCDKEYVSLGALKMHIRTHTLPCVCKICGKAFS 196
            |:|||||||.||:|.||.|    |.:||||||.|||.||||||||||||||||||.|.:||||||
  Fly   316 KSYSTFSGLTKHQQFHCPAAEGNQVKKSFSCKDCDKTYVSLGALKMHIRTHTLPCKCNLCGKAFS 380

Mouse   197 RPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKKYQCKNCSKTFSRMSLLHKHE 261
            ||||||||||||||||||||.||:||||||||||||||||||:|||.|.:|||||||||||.||.
  Fly   381 RPWLLQGHIRTHTGEKPFSCQHCHRAFADRSNLRAHLQTHSDIKKYSCTSCSKTFSRMSLLTKHS 445

Mouse   262 ESGC 265
            |.||
  Fly   446 EGGC 449

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Snai2NP_035545.1 SNAG domain. /evidence=ECO:0000250 1..20 1/2 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 81..117 8/40 (20%)
C2H2 Zn finger 131..151 CDD:275370 13/19 (68%)
C2H2 Zn finger 162..182 CDD:275368 17/19 (89%)
C2H2 Zn finger 188..208 CDD:275368 17/19 (89%)
zf-H2C2_2 201..224 CDD:290200 20/22 (91%)
zf-C2H2 214..236 CDD:278523 19/21 (90%)
C2H2 Zn finger 216..236 CDD:275368 17/19 (89%)
zf-H2C2_2 228..253 CDD:290200 20/24 (83%)
C2H2 Zn finger 244..260 CDD:275368 12/15 (80%)
esgNP_476600.1 zf-C2H2 309..331 CDD:278523 14/21 (67%)
C2H2 Zn finger 311..331 CDD:275370 13/19 (68%)
zf-C2H2 344..366 CDD:278523 19/21 (90%)
C2H2 Zn finger 346..366 CDD:275368 17/19 (89%)
zf-C2H2 370..392 CDD:278523 18/21 (86%)
C2H2 Zn finger 372..392 CDD:275368 17/19 (89%)
zf-H2C2_2 385..408 CDD:290200 20/22 (91%)
zf-C2H2 398..420 CDD:278523 19/21 (90%)
C2H2 Zn finger 400..420 CDD:275368 17/19 (89%)
C2H2 Zn finger 428..444 CDD:275368 12/15 (80%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 50 1.000 Domainoid score I11573
eggNOG 1 0.900 - - E1_KOG2462
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S1955
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0004977
OrthoInspector 1 1.000 - - mtm8700
orthoMCL 1 0.900 - - OOG6_107394
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3546
SonicParanoid 1 1.000 - - X955
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1110.650

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