Protein Alignment Slc5a1 and CG2187

DIOPT Version :10

• Sequence 1: NP_062784.3
• Gene: Slc5a1 / 20537
• MGIID: 107678
• Length: 665
• Species: Mus musculus
• Sequence 2: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Alignment Length: 530
• Identity: 133/530 - (25%)
• Similarity: 217/530 - (40%)
• Gaps: 84/530 - (15%)

Mouse     3 SSTLSPAVTATDAPIPSYERIR-NAADISVIVIYFVVVMAVGLW-AMFSTNRGTVGGFFLAGRSM 65
            |:|.:...|...|...:.:.:| ...|..|.||.......:|:: ..||.::.|...:...|:.|
  Fly     2 STTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKM 66

Mouse    66 VWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEW-----NALVLVVVLGWIFVPIYIKAGV 125
            ...||..||.||.:.     |:|.....|.....||.:     ..||::.:|.:|.||::.:..|
  Fly    67 QTLPIAISLVASQLS-----GIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNV 126

Mouse   126 VTMPEYLRKRFGGKRIQIYL------SVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFIL 184
            ....|||..||..:..|:..      |.|.|.:|:|....|       |..:. |::|:|...::
  Fly   127 SNCYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLA-------FAQVT-GMNIHLINVMV 183

Mouse   185 LAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNF 249
            .:|...||:.||:.||::||.:|.||||: |.:..|                  .:.|..|.|.|
  Fly   184 SSICIFYTMLGGIKAVVWTDVVQGAIMLL-SVVAVG------------------VLGTIRSGGMF 229

Mouse   250 TAKEECYTPRADSFHIFRDP----------ITGDMPWPGLIFGLAILALWYWCTDQVIVQRCLSA 304
            |..|........:|....||          :.|...|.|.| ||          :|..|||.:|.
  Fly   230 TVMERASDGGRFNFDFGLDPRIRMTFWGATMGGIFMWTGHI-GL----------NQSCVQRIVSL 283

Mouse   305 KNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTL 369
            .:.||.|....:.|...|:..|...:.|:|....|         ..|.......|...:...|..
  Fly   284 PSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARY---------YGCDPMLAGLVSKPDKMMPFF 339

Mouse   370 VVELMPN--GLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKKASEKELMIAGRLFILV 432
            |.::|.:  |:.|:.:|.:.::.:|||::..||.:.:...| |.|.|.:.:|.....|.:|.::|
  Fly   340 VQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFD-YIKPRIRHTEARANWAMKLIVVV 403

Mouse   433 LIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLILGFLIGI 497
            :.|..|....:||:..|  :...:.:||......:..||||.:|..|.|.:.|    :...::.:
  Fly   404 MGGYCILGGFMVQNFNS--ILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTA----VTSIIVSV 462

Mouse   498 SRMITEFAYG 507
            ..|:...|.|
  Fly   463 VAMVWIIANG 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a1	NP_062784.3	SLC5-6-like_sbd	27..665	CDD:444915	128/505 (25%)
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	128/505 (25%)