Protein Alignment Slc5a1 and CG5687

DIOPT Version :9

• Sequence 1: NP_062784.3
• Gene: Slc5a1 / 20537
• MGIID: 107678
• Length: 665
• Species: Mus musculus
• Sequence 2: NP_001286910.1
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Alignment Length: 585
• Identity: 139/585 - (23%)
• Similarity: 248/585 - (42%)
• Gaps: 116/585 - (19%)

Mouse    18 PSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSG 82
            ||::...:..|..:::...|:.:.:|::..|....|:....||.|..|..:|:..||..|.|.:
  Fly    90 PSHKATFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGSEMSIFPVTLSLTTSFITA- 153

Mouse    83 HFVGLAGTGAAAGIAMGGFEWNALVLVV--------VLGWIFVPIYIKAGVVTMPEYLRKRFGGK 139
              :.|.|..:..     .|:....||:|        |...||.|||.|..:.:..|||..|| ||
  Fly   154 --IELLGNPSEM-----YFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRF-GK 210

Mouse   140 RIQIYLSVLSLL-LYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYT 203
            .|:|..:||.:: :..:|.::  :.:.||.::.|.|||..:|:.::..:...|:..||:.||:..
  Fly   211 EIRILGAVLYVIQMCFYTAVA--VLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIA 273

Mouse   204 DTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTPRADSFHIFRD 268
            |:.|.|::.|...::.|            :..:....|.:|..   ||.:.   .|.:.|::..|
  Fly   274 DSFQAAVLAVSLVLIVG------------LGCFYSGNPIQVFQ---TASDH---NRLEFFNMDPD 320

Mouse   269 PITGDMPWPGLIFGLAILALWYW----CTDQVIVQRCLSAKN--MSHVKAGCTLCGYLKLLPMFL 327
            |.|....|..:|.|     .:||    ||:|..||:|:|.|:  ::.:..|..:.|   |:.:||
  Fly   321 PTTRHTVWSVVIGG-----FFYWTSLFCTNQASVQKCMSLKSLRLAKIALGFAIIG---LIVVFL 377

Mouse   328 MVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLVVELMP--NGLRGLMLSVMMASL 390
            :        ..||..:......:|.......:..|:...|..|:....  :.:.|:.::.:.|:.
  Fly   378 L--------NFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVINTYEHISSVAGIFVAGIFAAS 434

Mouse   391 MSSLTSIFNSASTLFTMDIYT-----KI--RKKASEKELMIAGRLFILVLIGI-SIAWVPIVQSA 447
            :.::.|..||.|.:...|:..     ||  .|.|:..:.|..|       .|| |...|.||:
  Fly   435 LGTVASALNSLSAVTCEDLLVNGMNIKISPEKGATYAKWMSLG-------FGIASFGLVFIVE-- 490

Mouse   448 QSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWG----LILGFLIGISRMITEFAYGT 508
            ..|.:.....::...:|.....:|:|.|.||:.|.:|||:|    |.|...:|:...|..
  Fly   491 HLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVGVVAQIVS----- 550

Mouse   509 GSCME----PSNCPKIICGVHYLYFAIILFVISVITILIISFLTKPIPDVH--------LYRLCW 561
               :|    |::..|..|.|:             :|.:|.|.||:|:..:.        ::||.:
  Fly   551 ---VEQPALPTSIDKCDCHVN-------------MTNIIGSLLTEPLEVIEEGGFTSWPIFRLSY 599

Mouse   562  561
              Fly   600  599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a1	NP_062784.3	SLC5-6-like_sbd	27..665	CDD:294310	137/576 (24%)
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	137/576 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810