Protein Alignment Slc5a1 and CG33124

DIOPT Version :10

• Sequence 1: NP_062784.3
• Gene: Slc5a1 / 20537
• MGIID: 107678
• Length: 665
• Species: Mus musculus
• Sequence 2: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 132/642 - (20%)
• Similarity: 246/642 - (38%)
• Gaps: 155/642 - (24%)

Mouse    28 DISVIVIYFVVVMAVGLW---------AMFSTNRGT------------VGGFFLAGRSMVWWPIG 71
            |.:|.:...::.:|:||:         .|.|:...|            :..:.:....:..:|:.
  Fly    10 DYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFPVA 74

Mouse    72 ASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVLVVVL-----GWIFVPIYIKAGVVTMPEY 131
            .||.||.|.     |:|..|..:.|...|.:::.:||.:|:     .:|::|::....|.:..||
  Fly    75 MSLIASFIS-----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEY 134

Mouse   132 LRKRFGG--KRIQIYLSVLSLLLYI-FTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTI 193
            |..||..  :.|...:.|:.:|||. |.     :|..|:.:|.|.||:|::...:::.:..:||:
  Fly   135 LGMRFHPLIRNIVSIMFVIEVLLYTPFV-----VFVPALALNQASGLNIHMIEVLIIVVCVIYTL 194

Mouse   194 TGGLAAVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTP 258
            .|||.||::||..|..||.....::...|                               .||..
  Fly   195 LGGLKAVVHTDIWQVVIMFASVVVVAILA-------------------------------TCYIT 228

Mouse   259 RADSFHIFRDPITGDMPWPGLIFG--------------LAILALWYW----CTDQVIVQRCLSAK 305
            ..|.|  |...:.|..    ||||              :.|...:||    ...|.:|.|.:|..
  Fly   229 DLDDF--FESLVDGGR----LIFGNINPSPYVRNTVWSVVIGGAFYWTSITAVHQTMVHRYMSLP 287

Mouse   306 NMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLV 370
            |:   |...|...:..|..:....:...:..:::.      :.::|.......:...:...|..|
  Fly   288 NL---KMARTSIAFFVLGSIIFYSVLSFLGLLIFN------MYKDCDPLSAGQIMNNDQLVPLFV 343

Mouse   371 VELMPN--GLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYT---KIRKKASEKELMIAGRLFI 430
            |:.:.:  |:.||.::.:..:.:|||:...||.|.:...||..   |::...:...:::..   .
  Fly   344 VQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKA---T 405

Mouse   431 LVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLILGFLI 495
            :|::|..:....::....|| :.....|:.:........:|.||:.....|..|...|.|.|||:
  Fly   406 IVIMGALVFGEVLLLEKVSG-ILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVGGIAGFLL 469

Mouse   496 -GISRMITEFAYGTGSC------MEPSNCPKIICGVHYLYF----AIILFVIS--------VITI 541
             |.....::.|..:|..      :..::||..:.....::.    ...||.:|        .:|:
  Fly   470 TGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHWINPIGALTV 534

Mouse   542 LI----ISFLTKPI-----------PDVH--LYRLCWSLRNSKEERIDLDAGEEEDI 581
            ::    :|.:|||.           |.:|  |.:.|:..||       ||..|..||
  Fly   535 VVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRN-------LDKSEATDI 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a1	NP_062784.3	SLC5-6-like_sbd	27..665	CDD:444915	132/642 (21%)
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	116/582 (20%)