DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc25a14 and CG1907

DIOPT Version :9

Sequence 1:	NP_001277634.1	Gene:	Slc25a14 / 20523	MGIID:	1330823	Length:	344	Species:	Mus musculus
Sequence 2:	NP_651703.1	Gene:	CG1907 / 43483	FlyBaseID:	FBgn0039674	Length:	317	Species:	Drosophila melanogaster

Alignment Length:	312	Identity:	102/312 - (32%)
Similarity:	166/312 - (53%)	Gaps:	19/312 - (6%)

- Green bases have known domain annotations that are detailed below.

Mouse    38 SSAELEQHQKSSTLSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIK 102
            |:..:::..|.:..::.:.      |::|||:.:.|.....|:||.|||:|:.|.....:    :
  Fly     2 SATSVQEAPKKAVATNAIK------FLFGGLSGMGATMVVQPLDLVKTRMQISGAGSGKK----E 56

Mouse   103 YRGMFHALFRIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLE-DETLLINMIC 166
            ||...|.:..|..:||.||||.||..||||||:|.|.::|:|..|..||.|:.: ...:..:|..
  Fly    57 YRSSLHCIQTIVSKEGPLALYQGIGAALLRQATYTTGRLGMYTYLNDLFREKFQRSPGITDSMAM 121

Mouse   167 GVVSGVISSTIANPTDVLKIRMQAQGSL------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQR 225
            |.::|...:.|..|.:|..:||.:.|.|      ...::..:...|.::||...||||.:||..|
  Fly   122 GTIAGACGAFIGTPAEVALVRMTSDGRLPVAERRNYTNVANALARITREEGLTALWRGSLPTVGR 186

Mouse   226 AAIVVGVELPVYDITKKHLIVSGM-LGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIV 289
            |.:|...:|..|...|.:.....: :.:.|..||.:|...||...:.|.|:|:.:||:.|.:.:.
  Fly   187 AMVVNMTQLASYSQFKTYFRHGPLQMEEGIKLHFCASMLSGLLTTITSMPLDIAKTRIQNMKMVD 251

Mouse   290 GHVDLYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 341
            |..: |:||.|.:|::.:.||.|||:|||.|.:.||||..::.||..|||.:
  Fly   252 GKPE-YRGTADVLLRVARQEGVFALWKGFTPYYCRLGPHTVLTFIILEQLNQ 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc25a14	NP_001277634.1	PTZ00169	63..342	CDD:240302	100/287 (35%)
Slc25a14	NP_001277634.1	Mito_carr	253..342	CDD:365909	36/89 (40%)
CG1907	NP_651703.1	Mito_carr	16..109	CDD:278578	39/102 (38%)
		Mito_carr	118..207	CDD:278578	25/88 (28%)
		Mito_carr	219..307	CDD:278578	35/85 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D892773at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860