Protein Alignment Slc22a12 and CG6356

DIOPT Version :9

• Sequence 1: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Sequence 2: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Alignment Length: 456
• Identity: 120/456 - (26%)
• Similarity: 200/456 - (43%)
• Gaps: 57/456 - (12%)

Mouse   106 TNWSDAATEPCEDGWVYDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRF 170
            |..|..|...|.....::.:...:|.|..|||.|:....|..||.....|...|:...|..:|:|
  Fly   125 TQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKF 189

Mouse   171 GRRRVLTWSYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLME--------WTSA 227
            ||:...|.......|......|.|.:.|:...||.|.:|.:|:.....::::|        |.|.
  Fly   190 GRKSSFTLGAAFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSI 254

Mouse   228 QGSPLVMTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKL 292
            ..|        ..:..|.::...|.|.::.||.||||::.|..|..:..:.:.||.|||||..:.
  Fly   255 AFS--------ASYPVGMIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRY 311

Mouse   293 DQGLQELQR----------VAAVNRRKAEGDTLTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLR 347
            |:..:.|.|          |||.::..::..:|           ||   :.|.|.|..|....|
  Fly   312 DRVYKILFRQPSHYQIQPAVAAPSQVASDKKSL-----------EP---EEGFSFGQKLKNGPL- 361

Mouse   348 HRTIISMLC-----------WFAF---GFTFYGLALDLQALGSNIFLLQALIGIVDFPVKTGSLL 398
             ::||.:..           :|.|   ..::|..||:...|..:.:|.....|:||.|.....::
  Fly   362 -KSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYIIGTGLVDIPSYLVPVI 425

Mouse   399 LISRLGRRLCQVSFLVLPGLCILSNILVPHGMGVLRSALAVLGLGCLGGAFTCITIFSSELFPTV 463
            ::...||||..:...:..|:.:|..:.||.|......|.|:||...:...::.:|::::||:||.
  Fly   426 MLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLGRFGISATYSVVTLYTAELYPTQ 490

Mouse   464 IRMTAVGLCQVAARGGAMLGP-LVRLLGVYGSWMPLLVYGVVPVLSGLAALLLPETKNLPLPDTI 527
            ||.:|:|.|...|..|::..| :|.:||..|.::|..:.|...:::||..|.||||....|.|.:
  Fly   491 IRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPETGTGKLSDKV 555

Mouse   528 Q 528
            :
  Fly   556 E 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	119/452 (26%)
		MFS	147..516	CDD:119392	103/401 (26%)
CG6356	NP_651240.1	MFS	167..544	CDD:119392	103/400 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843317
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.950