Protein Alignment Slc22a12 and CarT

DIOPT Version :9

• Sequence 1: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Sequence 2: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 579
• Identity: 158/579 - (27%)
• Similarity: 242/579 - (41%)
• Gaps: 106/579 - (18%)

Mouse     5 ELLDRVGGLGRFQLFQTVALVTPI---LWVTTQNMLENFSAAVP-HHRCWVP-LLDNSTSQ---A 61
            :||..:|..|::|......:..|.   ......|.|  |.|..| .:.|.:| |||....|   .
  Fly    38 DLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQL--FMADTPDDYWCRIPELLDLPLEQRKSL 100

Mouse    62 SIPGDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNA--TATNWSDAATEP---CEDGWV 121
            |||.:|..|.|:.           .:|..:.....||.||..  ..|.....|:.|   |..||.
  Fly   101 SIPKELDNDELVY-----------SKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWE 154

Mouse   122 YDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVS 186
            |:.|...|:||..:||||:......:..:....|..||..:.|..:||.|||    .||.:
  Fly   155 YNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRR----LSYFV---- 211

Mouse   187 GTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGS--------------PLVMTLN 237
                         |     ||:.:||.:|.:.|... ||.| ||              |.:::|.
  Fly   212 -------------C-----LATLLAGSLMTSLSKDF-WTWA-GSRVIVGLTIPAVYQIPFIISLE 256

Mouse   238 ALG--------------FSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLIT 288
            .:|              ::.|.:|...|.|..|.|..|....|.||:.:|:|.:.:|||.|||:.
  Fly   257 LVGENYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLM 321

Mouse   289 VGKLDQGLQELQRVAAVNRRKAEGDTLTMEVLRSAMEEEPSRDK--------AGASLGTLLHTPG 345
            .|:|::.|:.|:|:|.||.|:..      |.:...:|.:..|||        |...|..|..||.
  Fly   322 RGRLEEALKILERMAKVNGREFP------EAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPN 380

Mouse   346 LRHRTIISMLCWFA-----FGFTFYGLALDLQALGSNIFLLQALIGIVDFPVKTGSLLLISRLGR 405
            :|.:||:..|.|||     .|.::||     .|||:|.::...|..:|:.|........:...||
  Fly   381 MRLKTILITLSWFANETVYLGLSYYG-----PALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGR 440

Mouse   406 RLCQVSFLVLPGLCILSNILVPHGMGVLRSALAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVG 470
            |......::|.|:..:..:::|.........|.::....|..:|..|..|:.||:||.:|...:|
  Fly   441 RWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIG 505

Mouse   471 LCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAALLLPETKNLPLPDTIQD 529
            ........|.:..|.:..||.....:||::.|.:.:|.|:..|.||||.:..||.||::
  Fly   506 ASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEE 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	154/568 (27%)
		MFS	147..516	CDD:119392	107/409 (26%)
CarT	NP_610052.1	2A0119	44..561	CDD:273328	154/568 (27%)
		MFS	182..551	CDD:119392	107/407 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020