Protein Alignment Slc22a5 and CG6356

DIOPT Version :10

• Sequence 1: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Sequence 2: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 144/533 - (27%)
• Similarity: 236/533 - (44%)
• Gaps: 28/533 - (5%)

Mouse    11 LGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHR-CLVP--HTVNLSSAWRNHSIPLETK 72
            :|..|.|...||||.....|.|||:..|...|...|:.: |.:|  ...|.:.|.:...:.....
  Fly    31 VGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIVAKGLD 95

Mouse    73 DGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCLDGWEYDKDVFLSTIVTEWDLVCK 137
            .|...........||.::..:.|.. .|....:....:.||....:::.....:|.|.:|||.|.
  Fly    96 SGGCTVWDWNYGHLAKMSYEAALNY-TGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCD 159

Mouse   138 DDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVL 202
            ...:.........:|...|||..|.|:|:||||:...|........||...||..:.:|......
  Fly   160 RSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPWYSLFLAGRFA 224

Mouse   203 VGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPG 267
            :|......:..||.:..|.:....| .:.::.....|..|.::|.:..|.|:.||.|.||||:|.
  Fly   225 LGAASSGLFYPAFTMIVENICLKHR-SWMSIAFSASYPVGMIILAIVGYVIQPWRHLQLALTIPS 288

Mouse   268 VLCGALWWFIPESPRWLISQGRIKEA-EVIIRKAAKIN---GIVAPSTIFDPSELQDLNSTKPQ- 327
            :|.....:.:.|||||||:..|.... :::.|:.:...   .:.|||.:     ..|..|.:|:
  Fly   289 LLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQV-----ASDKKSLEPEE 348

Mouse   328 ------------LHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLA 380
                        |..|.:|.....:|.:...|..::...|:.|:..:|:..||....|:......
  Fly   349 GFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYIIGTG 413

Mouse   381 AVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITSAYSM 445
            .|::|:|::..::|::..||.:........|..||.:..||:.......|..|:|:|||::.||:
  Fly   414 LVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLGRFGISATYSV 478

Mouse   446 VYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFV-YLGAYDRFLPYILMGSLTILTAILTLFF 509
            |.:||||||||.:||..:|..||.:.:|||.:||.| .|||...::|..:.|...::..:|||..
  Fly   479 VTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTL 543

Mouse   510 PESFGVPLPDTID 522
            ||:....|.|.::
  Fly   544 PETGTGKLSDKVE 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	143/528 (27%)
CG6356	NP_651240.1	MFS_SLC22	140..544	CDD:340875	115/409 (28%)