Protein Alignment Slc22a5 and CG7458

DIOPT Version :9

• Sequence 1: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Sequence 2: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 163/539 - (30%)
• Similarity: 279/539 - (51%)
• Gaps: 40/539 - (7%)

Mouse     5 DEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSIPL 69
            |.:...:|::|.:|.:.:.||...::.|.|..:|.||.|.|..|||.||...:.||.:....:
  Fly    39 DAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWL-- 101

Mouse    70 ETKDGRQVPQK------CRRYRLATIANFSEL---GLEPGRDVDLEQ---LEQESCLDGWEY-DK 121
                |..:|:|      |.||    .||.|:.   ..:|.....|::   :..|:|...::: |:
  Fly   102 ----GFTIPKKNSAWDDCHRY----AANISDAISGYTDPSGQYCLKEYFTITSETCGRDFKFRDE 158

Mouse   122 DVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFL 186
            :   .||.||:.:.|:|:||..:..::..||..:|..:.|..:||:||:.:|.:...:......:
  Fly   159 E---KTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVI 220

Mouse   187 QVFSVNFEMFTVL-FVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFA 250
            :..|.|:.||.|. |:.:.:|. :.:..||:|..|::....|:..||: :.||||.|...|...|
  Fly   221 RSLSSNYSMFLVFEFLDMAVGS-TLFPTAFLLAIELVGPKRRVAAATI-ITIFYALGEAFLGFLA 283

Mouse   251 YFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDP 315
            ..::.||.||..|..|.||.....|.:|||.|||:|||..::|..::|:||:||....|.
  Fly   284 SQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPE----- 343

Mouse   316 SELQD-LNSTKPQLHHI----YDLIRTRNIRVITIMSIIL-WLTISVGYFGLSLDTPNLHGDIYV 374
            .:|.| |.|.:.:|...    |.::|......:.|.:..| |.|.::...||||::.||.|:.|.
  Fly   344 EQLNDLLTSNRQKLSQANESQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGNKYT 408

Mouse   375 NCFLLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGI 439
            |..|...:::|..:|..:::..:.||:|:.|::.|....:.....||::.:..|.||.::||..|
  Fly   409 NFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAI 473

Mouse   440 TSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAI 504
            |.::.::|.:|:|::||.|||..:.:.|...|:||:|:|....|..|..:.|.||..:..:::..
  Fly   474 TCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGF 538

Mouse   505 LTLFFPESFGVPLPDTIDQ 523
            |||.|||:....||.||::
  Fly   539 LTLAFPETADKVLPTTIEE 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	160/527 (30%)
		MFS	123..510	CDD:119392	122/393 (31%)
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	160/527 (30%)
		MFS	161..544	CDD:119392	122/389 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.980