Protein Alignment Slc22a5 and CarT

DIOPT Version :9

• Sequence 1: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Sequence 2: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 569
• Identity: 178/569 - (31%)
• Similarity: 289/569 - (50%)
• Gaps: 27/569 - (4%)

Mouse     3 DYDEVTAFLGEWGPFQRLIFF-LLSASIIPNGFNGMSIVFLAGTP-EHRCLVPHTVNLSSAWRNH 65
            |.|::...:||:|.:|:|:.| :...:.||.||...:.:|:|.|| ::.|.:|..::|....|..
  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKS 99

Mouse    66 -SIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQES------CLDGWEYDKDV 123
             |||.|..:...|..||..|.:    |:::| ||.|.:.||..:|..:      |..||||:..|
  Fly   100 LSIPKELDNDELVYSKCYTYGV----NWTQL-LESGEEDDLTTMEPNASWPLIKCPQGWEYNTSV 159

Mouse   124 FLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQV 188
            ..|:||.::||||..|....:..:....|..:|.::.|.|:||.||:...|:.:......|.:..
  Fly   160 VWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTS 224

Mouse   189 FSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFI 253
            .|.:|..:....|:||:...:.|...|::..|::.::.| .|.|:..|.||..|.|:|....|..
  Fly   225 LSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYR-SFVTVMTCTFYTSGIMLLSGVTYLE 288

Mouse   254 RDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSEL 318
            |||..|....::|........:.:|||||||:.:||::||..|:.:.||:||...|..:....|.
  Fly   289 RDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEA 353

Mouse   319 Q----DLNSTKPQLHHI--YDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCF 377
            |    .|...|.::.::  .||.||.|:|:.||:..:.|......|.|||...|.|..:.||:.|
  Fly   354 QIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFF 418

Mouse   378 LLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITSA 442
            |.|.||:|:|:..|..:....||:.:|.::.|||...:...::|.:....:..|.:|.|..::::
  Fly   419 LSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSAS 483

Mouse   443 YSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTL 507
            :.::|.:..|||||.||.:|:|.||....||.|..|:..|||..:..||.::||.|::|..:..|
  Fly   484 FLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGL 548

Mouse   508 FFPESFGVPLPDTIDQMLRVKGIKQWQIQSQTRMQKDGEESPTVLKSTA 556
            ..||:....||.||::.....  |.||.:...|.    .:.|.:|...|
  Fly   549 RLPETLHHRLPQTIEEGEEFG--KNWQFKDCCRC----AQKPEILSQPA 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	167/522 (32%)
		MFS	123..510	CDD:119392	124/392 (32%)
CarT	NP_610052.1	2A0119	44..561	CDD:273328	167/522 (32%)
		MFS	182..551	CDD:119392	115/369 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9078
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920