Protein Alignment Slc22a1 and CarT

DIOPT Version :9

• Sequence 1: NP_033228.2
• Gene: Slc22a1 / 20517
• MGIID: 108111
• Length: 556
• Species: Mus musculus
• Sequence 2: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 564
• Identity: 181/564 - (32%)
• Similarity: 288/564 - (51%)
• Gaps: 62/564 - (10%)

Mouse     4 VDDVLEHVGEFGWFQKQAFLLLCLISASLAPIYVGI-----VFLGFTPDHH-CRSPGVAE--LSQ 60
            :||:|..:||||.:||.....:||    .|.|..|.     :|:..|||.: ||.|.:.:  |.|
  Fly    36 LDDLLPTIGEFGKYQKLLVFGICL----PACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQ 96

Mouse    61 RCGWSPAEELNYTVPGLGSAGEASFLSQCMKYEVDWNQSTLDC--VDPLSSLAANRSHLPLSPCE 123
            |...|..:||:         .:....|:|..|.|:|.| .|:.  .|.|:::..|.| .||..|.
  Fly    97 RKSLSIPKELD---------NDELVYSKCYTYGVNWTQ-LLESGEEDDLTTMEPNAS-WPLIKCP 150

Mouse   124 HGWVYDTP--GSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLV 186
            .||.|:|.  .||||.:|:|||.......:..:.:|.|..:|..:.|.:.||.||:|...| .|.
  Fly   151 QGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFV-CLA 214

Mouse   187 TSLSG-VLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVGLV 250
            |.|:| ::|:::.|:.:....|::.|:.....:...:.:..|.||..||....::....:|.|::
  Fly   215 TLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIM 279

Mouse   251 GLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQAVRIMEQIAQKN-RKVP 314
            .|:||.|...||..|....|||.:.:.||.:.:||||||||.:.|..:|::|:|::|:.| |:.|
  Fly   280 LLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFP 344

Mouse   315 PA-DLKMMC------LEEDASERRSPSFADLFRTPSLRKHTLILMYLWFSCAVLYQGLIMHVGAT 372
            .| .||:..      |::...:..:...|||.|||::|..|:::...||:...:|.||..:..|.
  Fly   345 EAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPAL 409

Mouse   373 GANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVAGAACLLMIFIPHELHWLNVTLAC 437
            |.|.|:.||.|::||.|:.......:|..||.:|::.|.::.|.||::.:.:|.:
  Fly   410 GTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDD---------- 464

Mouse   438 LGRMGATIVLQMV--CLVNA----------ELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLME 490
              .:..|:||.:|  .|::|          |||||.:|.:|:...|.:..||.|..||:.: |.:
  Fly   465 --AVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITY-LGK 526

Mouse   491 VWQALPLILFGVLGLSAGAVTLLLPETKGVALPETIEEAENLGR 534
            ....|||::.|.|.:..|...|.||||....||:||||.|..|:
  Fly   527 DNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGK 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc22a1	NP_033228.2	2A0119	12..525	CDD:273328	172/545 (32%)
		MFS	125..515	CDD:119392	128/412 (31%)
CarT	NP_610052.1	2A0119	44..561	CDD:273328	172/545 (32%)
		MFS	182..551	CDD:119392	116/382 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920