Protein Alignment Slc1a5 and Eaat2

DIOPT Version :9

• Sequence 1: NP_033227.2
• Gene: Slc1a5 / 20514
• MGIID: 105305
• Length: 555
• Species: Mus musculus
• Sequence 2: NP_001162844.1
• Gene: Eaat2 / 33247
• FlyBaseID: FBgn0026438
• Length: 579
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 177/513 - (34%)
• Similarity: 293/513 - (57%)
• Gaps: 57/513 - (11%)

Mouse    47 RRCIRANLLVLLTVAAVVAGVGLGLGVSAAGGADALGPARL-----TAFAFPGELLLRLLKMIIL 106
            ||.:..||::|:|::.|:.||.|||         :|.|..|     ...::||||.:|:||::||
  Fly    43 RRWLSENLMLLVTLSGVLLGVILGL---------SLRPLNLHGDSIMLISYPGELFMRVLKLMIL 98

Mouse   107 PLVVCSLIGGAASLDPSALGRVGAWALLFFLVTTLLASALGVGLALALKPGAAVTAITSINDSVV 171
            |||:.|||.|:|||:....|::....|::|..|:...:|||:.|.|.:.||         |..:.
  Fly    99 PLVISSLIAGSASLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPG---------NPDLH 154

Mouse   172 DPCARSAPTKEV--LDSFLDLVRNIFPSNLVSAAFRSFATSYEPKDNSCKIPQSCIQREINSTM- 233
            :...||...:.|  |||.|||.||:||.||..|:.:...|.|.||.:...:    ....:|.|:
  Fly   155 NADDRSTDRRAVNLLDSLLDLGRNVFPDNLFQASIQQAHTVYLPKPSILHV----FNETMNDTLA 215

Mouse   234 ---------------VQLLCEVE---GMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDAT 280
                           |.|:.:::   |.|.||:|.|.:|||..|..:|.:|::::.||.:..:..
  Fly   216 SGSEAQRLSEDLTEDVVLVRDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVI 280

Mouse   281 MVLVSWIMWYAPVGILFLVASKIVEMKDVRQLFISLGKYILCCLLGHAIHGLLVLPLIYFLFTRK 345
            |.:|:.:||..||||..::|.||:.:.|:..:...|..:|:...:|..|:..:|:..|||:..|:
  Fly   281 MKMVTCVMWLTPVGISSVIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRR 345

Mouse   346 NPYRFLWGIMTPLATAFGTSSSSATLPLMMKCVEEKNGVAKHISRFILPIGATVNMDGAALFQCV 410
            ||::|..|::..:.|||.|:|::|.||:..:|:.||..|...|:||:||||..:||||.||:..|
  Fly   346 NPFKFYAGLIQAMLTAFATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAV 410

Mouse   411 AAVFIAQLNGVSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVSLPVKDISLILAVDW 475
            |::||||::|:.|.|.:::|:|:|:||:|:.:|.:|:..::.|.::|.|:..||:|::|:.||||
  Fly   411 ASIFIAQMSGMVLGFGELLTVLLTSTAASMSSASVPSAALVLLLVVLTAIDAPVQDVTLLFAVDW 475

Mouse   476 LVDRSCTVLNVEGDAFGAGLLQSYVDRTKMPSSEPELIQV-KNEVSLNPLPLATEEGN 532
            .|||..|..|:.||.:.|.:::..        |..||:.: ...|:...:|..|..|:
  Fly   476 FVDRIRTTNNMLGDCYTAAVVEEL--------SRKELMALDAASVNYQDMPAGTPNGH 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc1a5	NP_033227.2	SDF	55..496	CDD:278787	166/466 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	533..555		177/513 (35%)
Eaat2	NP_001162844.1	SDF	51..496	CDD:278787	166/466 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100309
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730