Sequence 1: | NP_004436.4 | Gene: | EPHB6 / 2051 | HGNCID: | 3396 | Length: | 1022 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_524625.3 | Gene: | Eph / 43803 | FlyBaseID: | FBgn0025936 | Length: | 1096 | Species: | Drosophila melanogaster |
Alignment Length: | 1130 | Identity: | 355/1130 - (31%) |
---|---|---|---|
Similarity: | 549/1130 - (48%) | Gaps: | 207/1130 - (18%) |
- Green bases have known domain annotations that are detailed below.
Human 1 MATEGAAQLGNRVAGMVCSLWVLLLVSSVLALEE--VLLDTTGETSEIGWLTYPPG------GWD 57
Human 58 EVSVLDDQRRLT-RTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSG 121
Human 122 GTCRETFTLYYRQ----AEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSSAAWAV 182
Human 183 GPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQ 247
Human 248 ASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGD 312
Human 313 KACQACPRGLYKASAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQE- 376
Human 377 -LWFEVQGSALMLHWRLP-------RELGGR---GDLLFNVVCKECEGRQEPASGGGGTCHRCRD 430
Human 431 EVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVV 495
Human 496 HQVSRASNSI------------------------------------------TVSWPQPDQTNGN 518
Human 519 ILDYQLRYYDQAE-DESHSFTLTSETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLP 582
Human 583 QGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRK-------RRGTGYTEQLQQYSS-- 638
Human 639 -------------------PGLG-VKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFG 683
Human 684 EVRQGRLQ--PRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLM 746
Human 747 VLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCK 811
Human 812 VARLG-----------HSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWD 865
Human 866 MSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTL---- 926
Human 927 ---QAGGD---PGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLS 985
Human 986 LEDLPALGITLAGHQKKLLHHIQLL 1010 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
EPHB6 | NP_004436.4 | EphR_LBD_B6 | 33..232 | CDD:198443 | 57/211 (27%) |
Ephrin_rec_like | 305..346 | CDD:311571 | 16/40 (40%) | ||
FN3 | 371..472 | CDD:238020 | 23/112 (21%) | ||
fn3 | 490..572 | CDD:306538 | 22/124 (18%) | ||
EphA2_TM | 613..665 | CDD:317033 | 22/80 (28%) | ||
PKc_like | 666..920 | CDD:328722 | 128/266 (48%) | ||
SAM_EPH-B6 | 946..1014 | CDD:188954 | 21/65 (32%) | ||
PDZ-binding. /evidence=ECO:0000255 | 1020..1022 | ||||
Eph | NP_524625.3 | EphR_LBD | 85..260 | CDD:198439 | 57/208 (27%) |
FN3 | 387..476 | CDD:238020 | 20/106 (19%) | ||
FN3 | 536..623 | CDD:238020 | 21/86 (24%) | ||
EphA2_TM | 644..736 | CDD:291255 | 26/93 (28%) | ||
PTKc_EphR | 736..1002 | CDD:270629 | 128/265 (48%) | ||
Pkinase_Tyr | 741..999 | CDD:285015 | 125/257 (49%) | ||
SAM_1 | 1033..1092 | CDD:278937 | 20/69 (29%) | ||
SAM | 1039..1092 | CDD:197735 | 19/52 (37%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 121 | 1.000 | Domainoid score | I5684 |
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 1 | 1.050 | 762 | 1.000 | Inparanoid score | I548 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D397694at33208 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0000086 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100189 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X82 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
8 | 7.870 |