| Sequence 1: | XP_016867305.1 | Gene: | EPHB4 / 2050 | HGNCID: | 3395 | Length: | 1005 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001153043.1 | Gene: | Ephb4 / 13846 | MGIID: | 104757 | Length: | 996 | Species: | Mus musculus |
| Alignment Length: | 1005 | Identity: | 920/1005 - (91%) |
|---|---|---|---|
| Similarity: | 950/1005 - (94%) | Gaps: | 9/1005 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQR 65
Human 66 APGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAW 130
Human 131 MENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYK 195
Human 196 KCAQLTVNLTRFPETVPRELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVTGCSCAPGFE 260
Human 261 AAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTDPRGAPCTTPPS 325
Human 326 APRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGGSCAPCGGDLTFDPGPRDLVEPW 390
Human 391 VVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREVKGQSYHAQGFPVSLPLTVPPAV 455
Human 456 SDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAELRGLKRGAS 520
Human 521 YLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLALIAGTAVVGVVLVLVVIVVAVLCLRKQS 585
Human 586 NGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRG 650
Human 651 RLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFME 715
Human 716 NGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLS 780
Human 781 RFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQ 845
Human 846 DVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENG 910
Human 911 GASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGH 975
Human 976 QKKILASVQHMKSQAKPGTPGGTGGPAPQY 1005 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| EPHB4 | XP_016867305.1 | EphR_LBD_B4 | 17..196 | CDD:198442 | 165/178 (93%) |
| FN3 | 324..429 | CDD:238020 | 91/104 (88%) | ||
| FN3 | 452..544 | CDD:238020 | 88/91 (97%) | ||
| EphA2_TM | <582..628 | CDD:291255 | 44/45 (98%) | ||
| PTKc_EphR_B | 628..896 | CDD:173638 | 266/267 (100%) | ||
| Pkinase_Tyr | 633..892 | CDD:285015 | 257/258 (100%) | ||
| SAM | 922..989 | CDD:197735 | 65/66 (98%) | ||
| SAM_EPH-B4 | 925..991 | CDD:188953 | 64/65 (98%) | ||
| Ephb4 | NP_001153043.1 | EphR_LBD_B4 | 17..196 | CDD:198442 | 165/178 (93%) |
| FN3 | 324..429 | CDD:238020 | 91/104 (88%) | ||
| FN3 | 443..535 | CDD:238020 | 88/91 (97%) | ||
| EphA2_TM | <571..619 | CDD:291255 | 46/47 (98%) | ||
| PTKc_EphR_B | 619..887 | CDD:173638 | 266/267 (100%) | ||
| Pkinase_Tyr | 624..883 | CDD:285015 | 257/258 (100%) | ||
| SAM | 913..980 | CDD:197735 | 65/66 (98%) | ||
| SAM_EPH-B4 | 916..982 | CDD:188953 | 64/65 (98%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 974..996 | 19/21 (90%) | |||
| PDZ-binding. /evidence=ECO:0000255 | 994..996 | 0/1 (0%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83972935 | |
| Domainoid | 1 | 1.000 | 526 | 1.000 | Domainoid score | I6811 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0196 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H20939 | |
| Inparanoid | 1 | 1.050 | 1889 | 1.000 | Inparanoid score | I1827 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG45908 | |
| OrthoDB | 1 | 1.010 | - | - | D29780at32523 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000086 | |
| OrthoInspector | 1 | 1.000 | - | - | oto124671 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100189 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24416 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R9273 |
| SonicParanoid | 1 | 1.000 | - | - | X82 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 18 | 18.300 | |||||