DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sin3b and hfp

DIOPT Version :9

Sequence 1:	XP_006530852.1	Gene:	Sin3b / 20467	MGIID:	107158	Length:	1119	Species:	Mus musculus
Sequence 2:	NP_525123.2	Gene:	hfp / 38173	FlyBaseID:	FBgn0028577	Length:	637	Species:	Drosophila melanogaster

Alignment Length:	162	Identity:	35/162 - (21%)
Similarity:	64/162 - (39%)	Gaps:	34/162 - (20%)

- Green bases have known domain annotations that are detailed below.

Mouse   477 VLETNLATIRVLESVQKKLSRMAPEDQEKLRLDDCLGGTSEVIQRRAIHRIYGDKAPEVIESLKR 541
            |...||:     |:::|...:...|.|:|| :|:   |..:.:|::....|.|..|.:::.....
  Fly   476 VTAANLS-----ENIKKAHEKQQEELQKKL-MDE---GDVQTLQQQENMSIKGQSARQLVMQRLM 531

Mouse   542 NPATAVPVVLKRLKAKE-------EEWREAQQGFNKIWREQY--EKAYLKSLDHQA-------VN 590
            .|..:..::|:.:...|       ||.:|....|..:.|...  ||......|.:|       |.
  Fly   532 RPVDSRVIILRNMVGPEDVDETLQEEIQEECSKFGTVSRVIIFNEKQTENEDDDEAEIIVKIFVE 596

Mouse   591 FKQNDTKALRSKSLLN--------EIESVYDE 614
            |... .:|:|.|..|:        .:..:||:
  Fly   597 FSAG-AEAMRGKEALDGRFFGGRRVVAELYDQ 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sin3b	XP_006530852.1	Sin3	40..1030	CDD:227889	35/162 (22%)
hfp	NP_525123.2	half-pint	10..637	CDD:130706	35/162 (22%)
		RRM1_PUF60	130..205	CDD:240816
		RRM2_PUF60	227..303	CDD:240817
		RRM3_UHM_PUF60	536..636	CDD:241092	19/93 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1.056642	Normalized mean entropy	S2096
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950