| Sequence 1: | NP_001291465.1 | Gene: | EPHA4 / 2043 | HGNCID: | 3388 | Length: | 986 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_031962.2 | Gene: | Epha4 / 13838 | MGIID: | 98277 | Length: | 986 | Species: | Mus musculus |
| Alignment Length: | 986 | Identity: | 972/986 - (98%) |
|---|---|---|---|
| Similarity: | 982/986 - (99%) | Gaps: | 0/986 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNT 65
Human 66 PIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESD 130
Human 131 NDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALV 195
Human 196 SVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNC 260
Human 261 LCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPC 325
Human 326 TRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQ 390
Human 391 NGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIALVQAKEVTRY 455
Human 456 SVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAG 520
Human 521 YGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADE 585
Human 586 EKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICV 650
Human 651 AIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKND 715
Human 716 GRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT 780
Human 781 TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPP 845
Human 846 PMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEF 910
Human 911 SAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQ 975
Human 976 MQQMHGRMVPV 986 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| EPHA4 | NP_001291465.1 | EphR_LBD_A4 | 30..203 | CDD:198450 | 169/172 (98%) |
| FN3 | 329..436 | CDD:238020 | 104/106 (98%) | ||
| FN3 | 441..532 | CDD:238020 | 90/90 (100%) | ||
| EphA2_TM | 562..618 | CDD:405290 | 55/55 (100%) | ||
| PTKc_EphR_A | 616..882 | CDD:270651 | 265/265 (100%) | ||
| SAM_EPH-A4 | 911..981 | CDD:188944 | 66/69 (96%) | ||
| PDZ-binding. /evidence=ECO:0000255 | 984..986 | 1/1 (100%) | |||
| Epha4 | NP_031962.2 | EphR_LBD_A4 | 30..203 | CDD:198450 | 169/172 (98%) |
| FN3 | 329..436 | CDD:238020 | 104/106 (98%) | ||
| FN3 | 441..532 | CDD:238020 | 90/90 (100%) | ||
| EphA2_TM | 562..616 | CDD:291255 | 53/53 (100%) | ||
| PTKc_EphR_A | 616..882 | CDD:270651 | 265/265 (100%) | ||
| Pkinase_Tyr | 621..878 | CDD:285015 | 256/256 (100%) | ||
| SAM_EPH-A4 | 911..981 | CDD:188944 | 66/69 (96%) | ||
| SAM | 915..975 | CDD:197735 | 56/59 (95%) | ||
| PDZ-binding. /evidence=ECO:0000255 | 984..986 | 1/1 (100%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83955974 | |
| Domainoid | 1 | 1.000 | 530 | 1.000 | Domainoid score | I6677 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0196 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H20933 | |
| Inparanoid | 1 | 1.050 | 1981 | 1.000 | Inparanoid score | I1651 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG45908 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000086 | |
| OrthoInspector | 1 | 1.000 | - | - | oto123892 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100189 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24416 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2895 |
| SonicParanoid | 1 | 1.000 | - | - | X82 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 17 | 17.290 | |||||