| Sequence 1: | NP_005223.4 | Gene: | EPHA1 / 2041 | HGNCID: | 3385 | Length: | 976 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_524625.3 | Gene: | Eph / 43803 | FlyBaseID: | FBgn0025936 | Length: | 1096 | Species: | Drosophila melanogaster |
| Alignment Length: | 1055 | Identity: | 370/1055 - (35%) |
|---|---|---|---|
| Similarity: | 537/1055 - (50%) | Gaps: | 157/1055 - (14%) |
- Green bases have known domain annotations that are detailed below.
|
Human 23 ARAKEVTLMDTSKAQGELGWLLDP--PK---DGWSEQQ--QILNGTPLYMYQDCPMQGRRDTDHW 80
Human 81 LRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRP----- 140
Human 141 -LFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRC 204
Human 205 PETLNGLAQFPDTLPGPAG----LVEVA-GTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCHC 264
Human 265 EPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRAPGEGPQVAC 329
Human 330 TGPPSAPRNLS-FSASGTQLSLRWEPPA-------DTGGR---QDVRYSVRCSQCQGTAQDGGPC 383
Human 384 QPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGS---SGHASTSVSIS---- 441
Human 442 ----------------MGHAESL---------SGLSLRLVKKEPRQLELTWAGSRPRSPGANLTY 481
Human 482 ---------ELHVLNQDEERYQMVLEPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSP 537
Human 538 PVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDR-------------ATDVD 589
Human 590 RED------KLWL----------KPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEV 638
Human 639 YRGTLRLPS---QDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMI 700
Human 701 ITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKV 765
Human 766 SDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEM 830
Human 831 SNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIAN 895
Human 896 FDPRMTLRLPSLSGS---DGIP----YRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDL 953
Human 954 TQMGITLPGHQKRIL 968 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| EPHA1 | NP_005223.4 | EphR_LBD_A1 | 27..203 | CDD:198447 | 62/188 (33%) |
| fn3 | 334..431 | CDD:278470 | 24/110 (22%) | ||
| FN3 | 453..535 | CDD:238020 | 19/90 (21%) | ||
| PKc_like | 619..884 | CDD:304357 | 150/267 (56%) | ||
| Pkinase_Tyr | 624..880 | CDD:285015 | 148/258 (57%) | ||
| SAM | 911..976 | CDD:197735 | 28/62 (45%) | ||
| SAM_EPH-A1 | 912..974 | CDD:188941 | 27/61 (44%) | ||
| PDZ-binding. /evidence=ECO:0000255 | 974..976 | ||||
| Eph | NP_524625.3 | EphR_LBD | 85..260 | CDD:198439 | 62/187 (33%) |
| FN3 | 387..476 | CDD:238020 | 22/101 (22%) | ||
| FN3 | 536..623 | CDD:238020 | 19/91 (21%) | ||
| EphA2_TM | 644..736 | CDD:291255 | 21/91 (23%) | ||
| PTKc_EphR | 736..1002 | CDD:270629 | 150/266 (56%) | ||
| Pkinase_Tyr | 741..999 | CDD:285015 | 148/258 (57%) | ||
| SAM_1 | 1033..1092 | CDD:278937 | 26/54 (48%) | ||
| SAM | 1039..1092 | CDD:197735 | 26/48 (54%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 55 | 1.000 | Domainoid score | I11113 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0196 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D397694at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100189 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24416 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X82 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 8 | 7.820 | |||||