Protein Alignment STOM and CG14736

DIOPT Version :10

• Sequence 1: NP_004090.4
• Gene: STOM / 2040
• HGNCID: 3383
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_731666.2
• Gene: CG14736 / 41466
• FlyBaseID: FBgn0037986
• Length: 473
• Species: Drosophila melanogaster
• Alignment Length: 289
• Identity: 127/289 - (43%)
• Similarity: 195/289 - (67%)
• Gaps: 18/289 - (6%)

Human     4 KRHTRDSEAQRLPDSF-------KDSPSK--GLGPCGWILVAFSFLFTVITFPISIWMCIKIIKE 59
            ||.:.|...:..|..:       |||..:  .:|.| |.||       :||||.|:..|:.|:.|
  Fly    29 KRPSADGGPRPPPSRYIQTSEDNKDSTFEKVAIGIC-WFLV-------IITFPFSMCCCLTIVPE 85

Human    60 YERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTISVDGVVYY 124
            |.|.||.|||| |:.|.:||||.|||||.|...:|||||...::.||::||||||||:|:.||||
  Fly    86 YSRMIILRLGR-LRKGLRGPGLVFILPCIDETHRVDMRTDVTNVRPQDVLTKDSVTITVNAVVYY 149

Human   125 RVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQSTLDDATDAWGIKV 189
            .:.:...::..:.:|..||:|::|.||||::|:|.|:.:|:.|::::..:|..:...|..||::|
  Fly   150 CIYSPIDSIIQVDDAKQATQLISQVTLRNIVGSKTLNVLLTSRQQLSREIQQAVAGITYRWGVRV 214

Human   190 ERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQ 254
            |||::.|:.||..|:|::|:||||.||||||:|.||||:.||:||||||.|::|:...||||:||
  Fly   215 ERVDVMDITLPTSLERSLASEAEAVREARAKIILAEGELKASKALKEASDVMSENKITLQLRHLQ 279

Human   255 TLTTIAAEKNSTIVFPLPIDMLQGIIGAK 283
            .|::||:|:...|::|:|:::::..:..|
  Fly   280 ILSSIASERRVRIIYPIPLEIMEPFMSGK 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STOM	NP_004090.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		5/24 (21%)
		SPFH_stomatin	73..274	CDD:259801	97/200 (49%)
		Required for homooligomerization	265..273		2/7 (29%)
		Required for lipid raft association	267..269		1/1 (100%)
		Interaction with LANCL1. /evidence=ECO:0000269|PubMed:9512664	273..287		1/11 (9%)
CG14736	NP_731666.2	SPFH_like	100..305	CDD:473137	97/204 (48%)