Protein Alignment STOM and CG31358

DIOPT Version :10

• Sequence 1: NP_004090.4
• Gene: STOM / 2040
• HGNCID: 3383
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_650147.1
• Gene: CG31358 / 41462
• FlyBaseID: FBgn0051358
• Length: 474
• Species: Drosophila melanogaster
• Alignment Length: 253
• Identity: 109/253 - (43%)
• Similarity: 176/253 - (69%)
• Gaps: 2/253 - (0%)

Human    33 ILVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMR 97
            :.|..|::..:|..|.|:..|:.|..|:.|.:|||||||  ....||||.|:|||.|||..||:|
  Fly    31 VAVFVSWILVLILLPFSLCCCLTIAYEFHRLVIFRLGRI--RSCLGPGLVFLLPCIDSFNTVDIR 93

Human    98 TISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQ 162
            |...::.|||:||||||:|:|:.||:|.:.:...::..:.:|..||..::|.||||::|:|.|.:
  Fly    94 TDVVNVDPQEMLTKDSVSITVNAVVFYCIYDPINSIIKVDDARDATERISQVTLRNIVGSKGLHE 158

Human   163 ILSDREEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGE 227
            :|:.|::::..:|..:...|:.||::||||::.::.||..|:|::|:||||:||||||:|.||||
  Fly   159 LLASRQQLSLEIQQAVAKITERWGVRVERVDLMEISLPSSLERSLASEAEATREARAKIILAEGE 223

Human   228 MNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGIIGAKHS 285
            ..||:||||.|.|::|:...||||:||.|.::|:|:...::||:|::::...:..|.|
  Fly   224 AKASKALKECSDVMSENQITLQLRHLQILCSMASERRVNVLFPIPLEIMAPFMDGKDS 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STOM	NP_004090.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		SPFH_stomatin	73..274	CDD:259801	91/200 (46%)
		Required for homooligomerization	265..273		2/7 (29%)
		Required for lipid raft association	267..269		0/1 (0%)
		Interaction with LANCL1. /evidence=ECO:0000269|PubMed:9512664	273..287		2/13 (15%)
CG31358	NP_650147.1	SPFH_like	74..276	CDD:473137	91/201 (45%)