Protein Alignment STOM and CG14644

DIOPT Version :10

• Sequence 1: NP_004090.4
• Gene: STOM / 2040
• HGNCID: 3383
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_649445.3
• Gene: CG14644 / 40536
• FlyBaseID: FBgn0250821
• Length: 293
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 117/247 - (47%)
• Similarity: 174/247 - (70%)
• Gaps: 0/247 - (0%)

Human    34 LVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRT 98
            |...|.:..|:..|.|::.|::::.|||||:|.||||:.....:|||:.|::||.|....||:||
  Fly    46 LFVLSMILIVLCLPWSLFCCLRVMSEYERAVILRLGRLRPKPPRGPGVIFLVPCIDDLAVVDIRT 110

Human    99 ISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQI 163
            .|||:..|||||:|.||||:||||||.:::...|:..:.:.:.||..||.||||||.||..|..:
  Fly   111 RSFDLHRQEILTRDMVTISIDGVVYYSIKSPFDAMLQVYDPEEATEKLAMTTLRNVAGTHKLMDL 175

Human   164 LSDREEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEM 228
            ||.:|.:::.::..|.::|:.|||:|||||||::.:|.||:||:|.|.||.|||:|||.||:||.
  Fly   176 LSSKEYLSNQIEGILYNSTEPWGIRVERVEIKEIFMPDQLKRALAVEQEAMREAKAKVAAAQGER 240

Human   229 NASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGII 280
            :|..|||||:.::..:|.||||||||||.:|..:...:.|||.|:|:::.::
  Fly   241 DAVTALKEAADIMETNPIALQLRYLQTLNSICNDDTRSYVFPFPVDIVRNLM 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STOM	NP_004090.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		SPFH_stomatin	73..274	CDD:259801	100/200 (50%)
		Required for homooligomerization	265..273		3/7 (43%)
		Required for lipid raft association	267..269		0/1 (0%)
		Interaction with LANCL1. /evidence=ECO:0000269|PubMed:9512664	273..287		1/8 (13%)
CG14644	NP_649445.3	SPFH_like	89..292	CDD:473137	101/202 (50%)