Protein Alignment AK2 and Ak1

DIOPT Version :10

• Sequence 1: NP_001616.1
• Gene: AK2 / 204
• HGNCID: 362
• Length: 239
• Species: Homo sapiens
• Sequence 2: NP_729792.1
• Gene: Ak1 / 39396
• FlyBaseID: FBgn0022709
• Length: 229
• Species: Drosophila melanogaster
• Alignment Length: 208
• Identity: 62/208 - (29%)
• Similarity: 100/208 - (48%)
• Gaps: 32/208 - (15%)

Human    20 LLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIE 84
            :||.||.|||||..::.|.:...||::||:||..|||||:.|::|:|.|.:|.|||::.|:.|:.
  Fly    37 ILGGPGCGKGTQCAKIVEKYGFTHLSSGDLLRNEVASGSDKGRQLQAVMASGGLVSNDEVLSLLN 101

Human    85 KNL-ETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKS 148
            ..: .......|||:||:||...|...    .|.|....|..:.|...:..:::||..|
  Fly   102 DAITRAKGSSKGFLIDGYPRQKNQGIE----FEARIAPADLALYFECSEDTMVQRIMAR------ 156

Human   149 GRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDAS 213
                               .....::|.|||||.::.||..:...|..::|.|..:.:  .|:|.
  Fly   157 -------------------AAASAVKRDDDNEKTIRARLLTFKQNTNAILELYEPKTL--TINAE 200

Human   214 QTPDVVFASILAA 226
            :..|.:|..::.|
  Fly   201 RDVDDIFLEVVQA 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AK2	NP_001616.1	Adk	17..226	CDD:440329	61/206 (30%)
		NMP. /evidence=ECO:0000255|HAMAP-Rule:MF_03168, ECO:0000269|Ref.17	45..74		14/28 (50%)
		LID. /evidence=ECO:0000255|HAMAP-Rule:MF_03168, ECO:0000269|Ref.17	141..178		2/36 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	150..169		0/18 (0%)
Ak1	NP_729792.1	aden_kin_iso1	30..217	CDD:130427	62/208 (30%)