Protein Alignment AK2 and Ak2

DIOPT Version :10

• Sequence 1: NP_001616.1
• Gene: AK2 / 204
• HGNCID: 362
• Length: 239
• Species: Homo sapiens
• Sequence 2: NP_523836.2
• Gene: Ak2 / 37834
• FlyBaseID: FBgn0283494
• Length: 240
• Species: Drosophila melanogaster
• Alignment Length: 233
• Identity: 155/233 - (66%)
• Similarity: 188/233 - (80%)
• Gaps: 5/233 - (2%)

Human     1 MAP--SVPAA--EPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELG 61
            |||  :||..  ||| ..||.|:||||||:|||||||.|.|.||||||:|||||||.::|||:||
  Fly     1 MAPNAAVPVERYEPE-NIGINAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISSGSKLG 64

Human    62 KKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVI 126
            .:||..|||||||||::||::|:.||:.|.||||||||||||||.|||.||.|::|||..||:||
  Fly    65 AELKKVMDAGKLVSDDLVVDMIDSNLDKPECKNGFLLDGFPRTVVQAEKLDTLLDKRKTNLDAVI 129

Human   127 EFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYH 191
            ||:|.||||:|||||||||..|||||||||.|||:||.||:||||||||||||.:|||.||:|||
  Fly   130 EFAIDDSLLVRRITGRLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYH 194

Human   192 TQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 229
            .||.||::||..||:|..:||::....||::|.:.|.:
  Fly   195 KQTKPLVDYYGLRGLHFKVDAAKKSSDVFSTIDSIFQR 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AK2	NP_001616.1	Adk	17..226	CDD:440329	144/208 (69%)
		NMP. /evidence=ECO:0000255|HAMAP-Rule:MF_03168, ECO:0000269|Ref.17	45..74		19/28 (68%)
		LID. /evidence=ECO:0000255|HAMAP-Rule:MF_03168, ECO:0000269|Ref.17	141..178		30/36 (83%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	150..169		14/18 (78%)
Ak2	NP_523836.2	Adk	20..229	CDD:440329	144/208 (69%)