Protein Alignment Sfrp1 and fz3

DIOPT Version :10

• Sequence 1: NP_038862.2
• Gene: Sfrp1 / 20377
• MGIID: 892014
• Length: 314
• Species: Mus musculus
• Sequence 2: NP_001096859.1
• Gene: fz3 / 31023
• FlyBaseID: FBgn0027343
• Length: 646
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 57/260 - (21%)
• Similarity: 90/260 - (34%)
• Gaps: 84/260 - (32%)

Mouse    91 KQQASSWVPLLNKNCHMGTQVFLCSLFAPVC---LDRPIYPCRWLCEAVRDSC-----EPVMQFF 147
            |.|.:..|||:...|....:..|||...|:|   :.||:..|:.|||.||..|     ..:|:.
  Fly   136 KGQIAKLVPLIESGCSRRARFLLCSSLFPLCTPDVPRPVAACKLLCETVRGECMENAPPELMEL- 199

Mouse   148 GFYWPEMLKCDKFPE---GDVCIAMTPPNTTEASKPQGTTVCPPCDNELKSEAIIEH-------- 201
               ||..|.||..|:   .::|:.:    ..|.:.|.|:...||...   |..:.:|
  Fly   200 ---WPSFLNCDGLPQPEKHELCMQI----PQEVAVPGGSPSGPPTTG---SPGVEDHPQTYRFWK 254

Mouse   202 ------------LC-----ASEFALRMKIKEVKKENGDKKIVPKKKKPLKLG------------- 236
                        ||     .|.|.....:.:.:::........|..:.|.||
  Fly   255 SGASPTSDLAGVLCPQNFSGSPFNPEECVPQCQRDAFHTSSQKKTSETLILGLSAVCFVLTLFAL 319

Mouse   237 ------PIKKKELKRLVLFLKNGADCPCHQLDNL-------------SHNFLIMGRKVKSQYLLT 282
                  |.:....:|.||||     |.|:.|.::             .|:..:..|.::...|||
  Fly   320 VTFWAEPTRFGYPERPVLFL-----CLCYNLFSVCYLERIVFHNQARMHDVELQWRLMRPGCLLT 379

Mouse   283  282
              Fly   380  379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfrp1	NP_038862.2	CRD_SFRP1	52..175	CDD:143552	28/94 (30%)
		NTR_Sfrp1_like	183..306	CDD:239635	26/157 (17%)
fz3	NP_001096859.1	RRM_1	22..83	CDD:425453
		CRD_FZ	<138..224	CDD:470581	27/93 (29%)
		7tmF_FZD3_insect	290..587	CDD:320159	18/95 (19%)
		TM helix 1	299..324	CDD:320159	3/24 (13%)
		TM helix 2	333..354	CDD:320159	8/25 (32%)
		TM helix 3	383..409	CDD:320159
		TM helix 4	426..442	CDD:320159
		TM helix 5	469..493	CDD:320159
		TM helix 6	513..540	CDD:320159
		TM helix 7	548..573	CDD:320159