DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Selenbp2 and CG7966

DIOPT Version :9

Sequence 1:	NP_062287.1	Gene:	Selenbp2 / 20342	MGIID:	104859	Length:	472	Species:	Mus musculus
Sequence 2:	NP_650256.2	Gene:	CG7966 / 41610	FlyBaseID:	FBgn0038115	Length:	486	Species:	Drosophila melanogaster

Alignment Length:	484	Identity:	240/484 - (49%)
Similarity:	336/484 - (69%)	Gaps:	14/484 - (2%)

- Green bases have known domain annotations that are detailed below.

Mouse     1 MATKCTKCGPGYPTPLEAMK-GPREEIVYLPCIYRNTGTEAPDYLATVDVDPKSPQYSQVIHRLP 64
            |:.|....||||.|||:||: ||||:::|...:..|......|||:||||||:||.|.|::||..
  Fly     1 MSNKTCCRGPGYATPLDAMRSGPREKLLYTVTVQPNLDEPHGDYLSTVDVDPESPTYCQIVHRTF 65

Mouse    65 MPYLKDELHHSGWNTCSSCF--GDSTKS---RNKLILPGLMSSRIYVVDVGSEPRAPKLHKVIEA 124
            .....|||||||||.||||:  .:|:|:   |::|:||.|.|..||::||.::||.|::.|.|:.
  Fly    66 TNRKGDELHHSGWNACSSCYYVDESSKTVPKRDRLVLPSLNSDFIYILDVVTDPRKPEIVKTIDG 130

Mouse   125 SEIQAKCNVSNTHTSHCLASGEVMVNTLGDLQGNGKGSFVLLDGETFEVKGTWEKPGGASPMGYD 189
            ..:::. ||:..||:||||:|.:|::.:||.:|..||.|:|.|.: |...|||.|....:..|||
  Fly   131 DVLKSH-NVTAPHTTHCLANGNIMISVMGDAEGYAKGDFILFDSD-FNCIGTWTKGDKKALCGYD 193

Mouse   190 FWYQPRHNVMVSTEWAAPNVFKDGFNPAHVE-AGLYGSRIFVWDWQRHEIIQTLQM-TDGLIPLE 252
            |||||..:||||:||.|||.::.|:....:| ...||.|:..:.|....:.||:.: :||:.|||
  Fly   194 FWYQPYFDVMVSSEWGAPNKWRRGWKNVDLEDMSQYGCRLNFYKWSTQTLYQTIDLGSDGITPLE 258

Mouse   253 IRFLHDPSATQGFVGCALSSNIQRF-YKNEEGTWSVEKVIQVPSKKVK--GWMLPEMPGLITDIL 314
            |||||:|...:|||||||::.:..| .|::...:..:|||.:|.|.|.  ..:..:|.|:|:||:
  Fly   259 IRFLHNPKKAEGFVGCALNAKVFHFKKKSDSDEFEAKKVIDIPGKLVDTGSGVAEDMGGMISDII 323

Mouse   315 LSLDDRFLYFSNWLHGDIRQYDISNPQKPRLTGQIFLGGSIVRG-GSVQVLEDQELTCQPEPLVV 378
            :||||||||.:.|.|||:|||||::|:.|:||||:||||:|... .:|.|.||:||..:|....|
  Fly   324 ISLDDRFLYVNCWRHGDVRQYDITDPENPKLTGQLFLGGAICSDLPNVIVKEDKELKERPPARYV 388

Mouse   379 KGKRIPGGPQMIQLSLDGKRLYATTSLYSDWDKQFYPDLIREGSVMLQVDVDTVNGGLKLNPNFL 443
            ||:|:.|||||:||||||||||.::||||.|||||||.::.:|..::.:||||||||:.||.:||
  Fly   389 KGRRLEGGPQMLQLSLDGKRLYVSSSLYSPWDKQFYPKMVSQGGHIVLIDVDTVNGGISLNEDFL 453

Mouse   444 VDFGKEPLGPALAHELRYPGGDCSSDIWI 472
            |||..||.||:|.||:|||||||:||||:
  Fly   454 VDFANEPYGPSLPHEMRYPGGDCTSDIWL 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Selenbp2	NP_062287.1	SBP56	7..472	CDD:283374	237/476 (50%)
CG7966	NP_650256.2	SBP56	6..482	CDD:283374	237/477 (50%)
CG7966	NP_650256.2	LVIVD repeat	321..358	CDD:293789	24/36 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843220
Domainoid	1	1.000	487	1.000	Domainoid score	I387
eggNOG	1	0.900	-	-		E1_KOG0918
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2930
Inparanoid	1	1.050	488	1.000	Inparanoid score	I1405
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61143
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003227
OrthoInspector	1	1.000	-	-		otm42483
orthoMCL	1	0.900	-	-		OOG6_104861
Panther	1	1.100	-	-	O	PTHR23300
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5418
SonicParanoid	1	1.000	-	-		X2649
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790