DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sele and hig

DIOPT Version :9

Sequence 1:	NP_035475.1	Gene:	Sele / 20339	MGIID:	98278	Length:	619	Species:	Mus musculus
Sequence 2:	NP_724773.1	Gene:	hig / 35949	FlyBaseID:	FBgn0010114	Length:	958	Species:	Drosophila melanogaster

Alignment Length:	328	Identity:	88/328 - (26%)
Similarity:	135/328 - (41%)	Gaps:	59/328 - (17%)

- Green bases have known domain annotations that are detailed below.

Mouse   182 EQAV----TCKPQEHPDYGSLNCSHPFGPFSYNSSCSFGCKRGYLPSSMETTVRCTSSGEWSAP- 241
            |:||    :.|..|:.|.|:..|:.|.|                |.:|:...|..::..:.:.|
  Fly   673 EKAVRYRLSIKNIENNDSGTFTCTSPRG----------------LTNSIAVVVATSTCPQLTEPL 721

Mouse   242 APACHVVECEALTHPAHGIRKCSSNPGSYPWNTTCTFDCVEGYRRVGAQNLQCTSSGIWDNETPS 306
            ||....:|...|...||                   ::|.||:|..||.|..|.:||.|.:.||:
  Fly   722 APLKLRLEGNKLGQRAH-------------------YECPEGFRLDGAWNATCLASGNWSSPTPT 767

Mouse   307 CKAVTCD--AIPQPQNGFVSCSHSTAGELAFKSSCNFTCEQSFTLQGPAQVECSAQGQWTPQIPV 369
            |.|:.|.  .:..|....:..:.|..|...||      |:..|.|.||||::|...|.|:..:|.
  Fly   768 CHAIQCPRLELDDPHLSLIELNTSAWGRAVFK------CQWGFKLTGPAQLDCEPSGVWSGPVPR 826

Mouse   370 CKAVQCEALSAPQQGNMKCLPSASGPFQNGSSCEFSCEEGFELKGSRRLQCGPRGEWDSKKPTCS 434
            ||.:||....||..|.:.....:......|:...|||.:|..|.|...:.|...|:|....|.|.
  Fly   827 CKVIQCVMPVAPLNGRIGGTSLSQRRLTVGALVTFSCNDGHSLVGESSIICTENGQWSHSPPFCK 891

Mouse   435 AVKCDDVPRPQNGVMECAHATTGEFTYKSS--CAFQCNEGF--SLHGSAQL-ECTSQGKWTQEVP 494
            : :|.....|.||::     ...:|.|.:.  .:.||..||  |..|..:. :|...|:|:..:|
  Fly   892 S-QCPYPGDPPNGLI-----APLKFNYDAGDYLSVQCRPGFVQSYEGPPERPKCQPDGRWSGPMP 950

Mouse   495 SCQ 497
            .|:
  Fly   951 KCK 953

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sele	NP_035475.1	CLECT_selectins_like	29..147	CDD:153062
		EGF_CA	<155..182	CDD:238011	88/328 (27%)
		CCP	187..245	CDD:153056	13/58 (22%)
		PHA02927	269..496	CDD:222943	67/233 (29%)
		CCP	501..556	CDD:153056
hig	NP_724773.1	PHA02927	705..952	CDD:222943	75/277 (27%)
		CCP	714..768	CDD:153056	20/72 (28%)
		CCP	<795..828	CDD:153056	13/38 (34%)
		CCP	832..891	CDD:153056	15/58 (26%)
		Sushi	894..952	CDD:278512	16/62 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12216
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19325
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.100