DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sfrp2 and fz

DIOPT Version :9

Sequence 1:	NP_033170.1	Gene:	Sfrp2 / 20319	MGIID:	108078	Length:	295	Species:	Mus musculus
Sequence 2:	NP_001261836.1	Gene:	fz / 45307	FlyBaseID:	FBgn0001085	Length:	612	Species:	Drosophila melanogaster

Alignment Length:	164	Identity:	53/164 - (32%)
Similarity:	78/164 - (47%)	Gaps:	10/164 - (6%)

- Green bases have known domain annotations that are detailed below.

Mouse    19 LGSARGLFLFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLV 83
            |.::.|..|.|.|    ..:.|:||  .:.:|..|.|....:|||:||...:|...:...:.|||
  Fly    36 LMASSGTELDGLP----HHNRCEPI--TISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLV 94

Mouse    84 MKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFP-- 146
            ...|..|.:.|||||:.||| ..|:..|.||.|||...: .|..:|..:.|.||:.|||.:||
  Fly    95 KIGCSDDLQLFLCSLYVPVC-TILERPIPPCRSLCESAR-VCEKLMKTYNFNWPENLECSKFPVH 157

Mouse   147 QDNDLCIPLASSDHLLPATEEAPKVCEACKTKNE 180
            ...|||:...::.....|......|.:....|::
  Fly   158 GGEDLCVAENTTSSASTAATPTRSVAKVTTRKHQ 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sfrp2	NP_033170.1	CRD_SFRP2	36..163	CDD:143555	45/128 (35%)
Sfrp2	NP_033170.1	NTR_Sfrp1_like	169..295	CDD:239635	2/12 (17%)
fz	NP_001261836.1	CRD_FZ1_like	51..167	CDD:143567	45/119 (38%)
fz	NP_001261836.1	Frizzled	237..564	CDD:279827
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810