DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Serpinf1 and Spn42Dd

DIOPT Version :9

Sequence 1:	NP_035470.3	Gene:	Serpinf1 / 20317	MGIID:	108080	Length:	417	Species:	Mus musculus
Sequence 2:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	115/381 - (30%)
Similarity:	184/381 - (48%)	Gaps:	34/381 - (8%)

- Green bases have known domain annotations that are detailed below.

Mouse    50 VNKLAAAVSNFGYDLYRLRSSASPTGNVLLSPLSVATALSALSLGAEHRTESVIHRALYYDLITN 114
            |..:|...|.   ::|:|.|.:....|:::||:|:.|.||.:.:|||..|...:..||.......
  Fly    10 VTSVACQTSK---EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDK 71

Mouse   115 PDIHSTYKELLASVTAPEKN--LKSASRIVFERKLRVKSSFVAPLEKSYGTRPR--ILTGNPRVD 175
            ..:.:.|..||..:...|:.  ||.|:||....:..:..::...:.:.:.:...  .||..| |.
  Fly    72 EAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGP-VA 135

Mouse   176 LQEINNWVQAQMKGKIAR--STREMPSALSILLLGVAYFKGQWVTKFDSRKTTLQDFHLDEDRTV 238
            .:.||.||..|..|||..  ....|.|.:..||:...||||||.:|||..||....|.:..:::|
  Fly   136 AERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSV 200

Mouse   239 RVPMMSDPKAILRYGLDSDLNCKIAQLP-LTGSMSIIFFLPLTVTQNLTMIEESLTSEFIHDIDR 302
            .|.||:. ....|.....||:.::.:|| |..::|:..|||..| :.|:.:||.:..     ..|
  Fly   201 PVQMMAQ-MGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREV-EGLSALEEKIVG-----FAR 258

Mouse   303 ELKTIQAVLTVPKLKLSFEGELTKSLQDMKLQSLFESPDFSKITG-----KPVKLTQVEHRAAFE 362
            .|...:..|.:||.|:.|..||.::|:.:.::.||  .|.|.::|     ...|::||.|:|..|
  Fly   259 PLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELF--TDKSDLSGLFADKSGGKVSQVSHKAFLE 321

Mouse   363 WNEEGAGSSPSPGLQPVRLT----FPLDYHLNQPFLFVLRDTDTGALLFIGRILDP 414
            .|||||.::   |...|.:|    |......:.||.||:||.:|  :.|.||::.|
  Fly   322 VNEEGAEAA---GATSVAVTNRAGFSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Serpinf1	NP_035470.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	17..41
Serpinf1	NP_035470.3	PEDF	39..414	CDD:239007	114/379 (30%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	111/370 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010