Protein Alignment TUBB and alphaTub84D

DIOPT Version :9

• Sequence 1: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_524264.1
• Gene: alphaTub84D / 40904
• FlyBaseID: FBgn0003885
• Length: 450
• Species: Drosophila melanogaster
• Alignment Length: 458
• Identity: 179/458 - (39%)
• Similarity: 268/458 - (58%)
• Gaps: 20/458 - (4%)

Human    15 RSGVRDHPGQQSETLPHATFLQKIKFWEVISDEHGIDPTGTYHGDSDL--QLDRISVYYNEATGG 77
            |..:..|.||....:.:|.       ||:...||||.|.|....|..:  ..|..:.:::|...|
  Fly     2 RECISIHVGQAGVQIGNAC-------WELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAG 59

Human    78 KYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRK 142
            |:||||:.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|:||.|||.:||
  Fly    60 KHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRK 124

Human   143 EAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATL 207
            .|:.|..||||.:.||.|||||||..:||:.::..:|..:....|:|.|:|:||..||||||:.|
  Fly   125 LADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSIL 189

Human   208 SVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRK 272
            :.|..:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:
  Fly   190 TTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTE 254

Human   273 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVF 337
            ...|:||:||:||.:..:||:.|.....:..|:|.|:|...|:..|.|...|||||:|:....::
  Fly   255 FQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMACCMLY 319

Human   338 RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTFIGNSTAI 394
            ||.:..|:|:..:..::.|.:..||:|.|...|..:...||        ..::.||..:.|:|||
  Fly   320 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAI 384

Human   395 QELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEE 459
            .|.:.|:..:|..|:.::||:|||.||||:|.||:||.   .||.:..:.|::...:..:..||.
  Fly   385 AEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAR---EDLAALEKDYEEVGMDSGDGEGEG 446

Human   460 AEE 462
            |||
  Fly   447 AEE 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	169/419 (40%)
		beta_tubulin	39..446	CDD:276956	168/416 (40%)
alphaTub84D	NP_524264.1	PTZ00335	1..439	CDD:185562	174/446 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810