Protein Alignment TUBB and alphaTub67C

DIOPT Version :9

• Sequence 1: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_524009.2
• Gene: alphaTub67C / 39130
• FlyBaseID: FBgn0087040
• Length: 462
• Species: Drosophila melanogaster
• Alignment Length: 443
• Identity: 174/443 - (39%)
• Similarity: 258/443 - (58%)
• Gaps: 27/443 - (6%)

Human    41 WEVISDEHGIDPTG--------TYHGDS-----DLQLDRISVYYNEATGGKYVPRAILVDLEPGT 92
            ||:...||||:..|        |..|.|     |...:....::.|...||.|||:|.|||||..
  Fly    21 WELYLLEHGINLDGSLKTKEELTASGSSASVGHDTSANDARTFFTETGNGKQVPRSIFVDLEPTV 85

Human    93 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTH 157
            :|.||:|...:::.|:..:.|:..|.||:|:|.|:.|.|::|.|...::|.||.||.||||.:.|
  Fly    86 IDDVRNGCMRELYHPEQLISGKEDAANNYARGRYSIGKEVIDRVTSRLQKIAEQCDSLQGFLIFH 150

Human   158 SLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCI 222
            |||||||||..:||:.::..:|..:....|:|.||||||..|||||||.|:.|..::::|..:.:
  Fly   151 SLGGGTGSGFTSLLVERLSTDYSKKCKLDFAVYPSPKVSTAVVEPYNALLTTHSTMDHSDCVFMV 215

Human   223 DNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 287
            ||||:||||..:|.:..|.|.:||.|::..:|..|..|||.|.:|.||.:...|:|||||:||.:
  Fly   216 DNEAIYDICNNSLGVDRPAYRNLNRLIAQIVSSTTASLRFSGSMNVDLNEFQTNLVPFPRIHFPL 280

Human   288 PGFAPLTS--RGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM 350
            ..:|||.|  |.:.:..|:|.  ||...|::.|||..||||.|:::....::||.:..|:|:..:
  Fly   281 VAYAPLMSAERSAHEQHAITT--LTNACFESSNMMVKCDPRAGKFMACCMLYRGDVVPKDVNAAV 343

Human   351 LNVQNKNSSYFVEWIPNNVKTAV-----CDIPPRGL---KMAVTFIGNSTAIQELFKRISEQFTA 407
            ..:::|....||:|.|...|..:     ..:|...|   ..|...:.|:|||...|..:|.:|..
  Fly   344 SAIKSKRHIQFVDWCPTGFKIGINYEKPAFVPDGDLAKTSRACCMLSNTTAISVAFSNLSYKFDL 408

Human   408 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEE--EEDFGE 458
            ||:::||:|||.||||:|.|||||..|:..|..::::.....|||  :|||.|
  Fly   409 MFKKRAFVHWYVGEGMEEGEFTEARENIAVLERDFEEVGLDNAEEGGDEDFDE 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	167/430 (39%)
		beta_tubulin	39..446	CDD:276956	167/427 (39%)
alphaTub67C	NP_524009.2	alpha_tubulin	2..446	CDD:276955	167/426 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810