Protein Alignment TUBB and betaTub60D

DIOPT Version :10

• Sequence 1: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0288686
• Length: 454
• Species: Drosophila melanogaster
• Alignment Length: 431
• Identity: 384/431 - (89%)
• Similarity: 410/431 - (95%)
• Gaps: 8/431 - (1%)

Human    39 KFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEA------TGGKYVPRAILVDLEPGTMDSVR 97
            ||||:||:|||||..|.|.|||||||:|:|||||||      :||||||||||:|||||||:|||
  Fly    19 KFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKYVPRAILLDLEPGTMESVR 83

Human    98 SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGG 162
            |||:||:|||||||:||||||||||||||||||||||:||||||||.|:||||||||||||||||
  Fly    84 SGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKECENCDCLQGFQLTHSLGGG 148

Human   163 TGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEAL 227
            ||||||||||||||||||||||||:|||||||||||||||||||||:||||||||||||||||||
  Fly   149 TGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEAL 213

Human   228 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 292
            |||||||||::.|:|||||||||.|||||||||||||||||||||||||||||||||||||||||
  Fly   214 YDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 278

Human   293 LTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKN 357
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||.|||||
  Fly   279 LTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLAVQNKN 343

Human   358 SSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEG 422
            |||||||||||||||||||||:||||:.|||||:||||||||||||||:||||||||||||||||
  Fly   344 SSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQFSAMFRRKAFLHWYTGEG 408

Human   423 MDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEE 463
            ||||||||||||||||||||||||:|||::|  |..|..:|
  Fly   409 MDEMEFTEAESNMNDLVSEYQQYQEATADDE--FDPEVNQE 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	377/415 (91%)
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	384/431 (89%)