Protein Alignment TUBB and betaTub56D

DIOPT Version :9

• Sequence 1: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_725896.1
• Gene: betaTub56D / 37238
• FlyBaseID: FBgn0284243
• Length: 456
• Species: Drosophila melanogaster
• Alignment Length: 424
• Identity: 402/424 - (94%)
• Similarity: 416/424 - (98%)
• Gaps: 0/424 - (0%)

Human    40 FWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQI 104
            |||:||||||||.||.|||||||||:||:||||||:||||||||:||||||||||||||||||||
  Fly    29 FWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQI 93

Human   105 FRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGT 169
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly    94 FRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGT 158

Human   170 LLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRT 234
            |||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||
  Fly   159 LLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRT 223

Human   235 LKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQ 299
            ||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   224 LKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQ 288

Human   300 QYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEW 364
            |||||||||||||:||||||||||||||||||||||:||||||||||||||||:|||||||||||
  Fly   289 QYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEW 353

Human   365 IPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 429
            |||||||||||||||||||:.||||||||||||||||||||||||||||||||||||||||||||
  Fly   354 IPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFT 418

Human   430 EAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEE 463
            |||||||||||||||||:|||:|:.:|.||.|.|
  Fly   419 EAESNMNDLVSEYQQYQEATADEDAEFEEEQEAE 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	393/408 (96%)
		beta_tubulin	39..446	CDD:276956	391/405 (97%)
betaTub56D	NP_725896.1	beta_tubulin	26..435	CDD:276956	391/405 (97%)
		PLN00220	29..438	CDD:215107	393/408 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	426	1.000	Domainoid score	I606
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	884	1.000	Inparanoid score	I397
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D259639at33208
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2834
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.910