Protein Alignment TUBB and gammaTub23C

DIOPT Version :9

• Sequence 1: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_476804.1
• Gene: gammaTub23C / 33501
• FlyBaseID: FBgn0260639
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 441
• Identity: 148/441 - (33%)
• Similarity: 250/441 - (56%)
• Gaps: 32/441 - (7%)

Human    39 KFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQ 103
            :||:.:..||||.|:|.....::..|||..|::.:|....|:|||:|:||||..::::....:.:
  Fly    20 EFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLDLEPRVINTIMGSVYSK 84

Human   104 IFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSG 166
            ::.|:|....:  .|||||||.| |::|.:|.:.|.|::.:||:..|.|:||.|.||:.||||||
  Fly    85 LYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSDSLEGFILCHSIAGGTGSG 148

Human   167 MGTLLISKIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 230
            ||:.::.::.:.||.:::.||||.|: .::||.||:|||:.|::.:|....|....:||.||..|
  Fly   149 MGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTTAADSVVVLDNTALNRI 213

Human   231 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTS 295
            ....|.:..|::..:|:|||..||..||.||:|..:|.:|..|...::|.|:|||.|.|:.||||
  Fly   214 ACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIPTPQLHFLMTGYTPLTS 278

Human   296 RG---SQQ---YRALTVPELTQQVFDAKNMMAACDP---RHGRYLTVAAVFRGRMSMKEVDEQML 351
            ..   :||   .|..||.::.:::...||||.:..|   .|..|:::..:.:|.:...:|.:.:.
  Fly   279 DSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISILNIIQGEVDPTQVHKSLQ 343

Human   352 NVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTFIGNSTAIQELFKRISEQFTAM 408
            .::::..:.|:.|.|.:::.|:....|        .||.:|     |.|:|..||:|...|:..:
  Fly   344 RIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLA-----NHTSICSLFERALNQYDKL 403

Human   409 FRRKAFLHWYTGEGM---DEMEFTEAESNMNDLVSEYQQYQDATAEEEEDF 456
            .:|.|||..:..|.:   |..|..|:...::.||   |:|:.||.|:...|
  Fly   404 RKRGAFLDQFRREDIFKDDLNELDESRETVDCLV---QEYEAATREDYMQF 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	144/432 (33%)
		beta_tubulin	39..446	CDD:276956	143/429 (33%)
gammaTub23C	NP_476804.1	PLN00222	1..451	CDD:215108	147/439 (33%)
		gamma_tubulin	4..440	CDD:276957	143/428 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810