Protein Alignment TUBB and gammaTub23C

DIOPT Version :10

• Sequence 1: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_476804.1
• Gene: gammaTub23C / 33501
• FlyBaseID: FBgn0260639
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 441
• Identity: 148/441 - (33%)
• Similarity: 250/441 - (56%)
• Gaps: 32/441 - (7%)

Human    39 KFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQ 103
            :||:.:..||||.|:|.....::..|||..|::.:|....|:|||:|:||||..::::....:.:
  Fly    20 EFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLDLEPRVINTIMGSVYSK 84

Human   104 IFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSG 166
            ::.|:|....:  .|||||||.| |::|.:|.:.|.|::.:||:..|.|:||.|.||:.||||||
  Fly    85 LYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSDSLEGFILCHSIAGGTGSG 148

Human   167 MGTLLISKIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 230
            ||:.::.::.:.||.:::.||||.|: .::||.||:|||:.|::.:|....|....:||.||..|
  Fly   149 MGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTTAADSVVVLDNTALNRI 213

Human   231 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTS 295
            ....|.:..|::..:|:|||..||..||.||:|..:|.:|..|...::|.|:|||.|.|:.||||
  Fly   214 ACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIPTPQLHFLMTGYTPLTS 278

Human   296 RG---SQQ---YRALTVPELTQQVFDAKNMMAACDP---RHGRYLTVAAVFRGRMSMKEVDEQML 351
            ..   :||   .|..||.::.:::...||||.:..|   .|..|:::..:.:|.:...:|.:.:.
  Fly   279 DSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISILNIIQGEVDPTQVHKSLQ 343

Human   352 NVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTFIGNSTAIQELFKRISEQFTAM 408
            .::::..:.|:.|.|.:::.|:....|        .||.:|     |.|:|..||:|...|:..:
  Fly   344 RIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLA-----NHTSICSLFERALNQYDKL 403

Human   409 FRRKAFLHWYTGEGM---DEMEFTEAESNMNDLVSEYQQYQDATAEEEEDF 456
            .:|.|||..:..|.:   |..|..|:...::.||   |:|:.||.|:...|
  Fly   404 RKRGAFLDQFRREDIFKDDLNELDESRETVDCLV---QEYEAATREDYMQF 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	144/432 (33%)
gammaTub23C	NP_476804.1	gamma_tubulin	4..440	CDD:276957	143/428 (33%)