Protein Alignment TUBB and CG32396

DIOPT Version :9

• Sequence 1: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_729172.1
• Gene: CG32396 / 117406
• FlyBaseID: FBgn0052396
• Length: 462
• Species: Drosophila melanogaster
• Alignment Length: 438
• Identity: 229/438 - (52%)
• Similarity: 308/438 - (70%)
• Gaps: 19/438 - (4%)

Human    40 FWEVISDEHGID-PTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQ 103
            ||.|||.|||:| .:|.:.|.|.|||:||:|::|.....::..|.||:|.|..|:..:.:.  .|
  Fly    20 FWHVISHEHGVDYASGRFGGTSPLQLERINVFFNATASKRFYARTILIDTEASTIQRLNAS--SQ 82

Human   104 IFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMG 168
            ::||:|||.|...||||:|:|::|:||.::|.||:..|:|.||.|.||||||.||:|||||||:.
  Fly    83 LYRPENFVAGSESAGNNFARGYHTDGAAILDQVLENTRREVESVDSLQGFQLLHSIGGGTGSGLT 147

Human   169 TLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFR 233
            :|::..:.|:|||.::..:..:|||.:|..|||||||.||...||.|:..|:|:|||||:.||.|
  Fly   148 SLIMEALVEQYPDNLLCNYVTIPSPNMSQVVVEPYNALLSTPALVNNSHLTFCLDNEALFQICNR 212

Human   234 TLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 298
            .|||....|..:||:|:.||||:||||||||||||.|||:.|||||||||||.:||||||.:...
  Fly   213 NLKLKMSGYEHINHIVALTMSGITTCLRFPGQLNAGLRKIYVNMVPFPRLHFLIPGFAPLVTCKQ 277

Human   299 QQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVE 363
            ||:...||.||.||:|.:.|::.|.|.|.|:.||.|.:||||||.:|||:.|..|:|||.:.||:
  Fly   278 QQFSKGTVSELVQQIFYSNNLLCAIDLRKGKLLTAAGIFRGRMSPREVDQLMTGVRNKNINNFVD 342

Human   364 WIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEF 428
            |||||:|||:||||||||||:.|||||:||||.||:|:.:...:|.||||.|||||||||:|.||
  Fly   343 WIPNNIKTAICDIPPRGLKMSATFIGNTTAIQTLFQRLLDASMSMLRRKAHLHWYTGEGMEEQEF 407

Human   429 TEAESNMNDLVSEYQQYQDATAEEEEDFG------------EEAEEEA 464
            .:|:..:..::.:|:    ::||.|:..|            |..||||
  Fly   408 QDAQQELQAIIDDYR----SSAEGEDSGGGGGGGGGRSGSAESGEEEA 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	220/409 (54%)
		beta_tubulin	39..446	CDD:276956	220/406 (54%)
CG32396	NP_729172.1	PTZ00010	1..421	CDD:240228	219/402 (54%)
		beta_tubulin	2..425	CDD:276956	220/410 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D962471at2759
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920