Protein Alignment ADCK5 and D2023.6

DIOPT Version :9

• Sequence 1: XP_011515209.1
• Gene: ADCK5 / 203054
• HGNCID: 21738
• Length: 654
• Species: Homo sapiens
• Sequence 2: NP_505980.1
• Gene: D2023.6 / 179618
• WormBaseID: WBGene00008410
• Length: 512
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 172/515 - (33%)
• Similarity: 275/515 - (53%)
• Gaps: 42/515 - (8%)

Human   122 RKVLSTAVVGAPLLLG-------ARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCT 179
            ||:|:...:...|.:|       ..|.:....:.|::     |:.||||:.....:|.:||
 Worm     4 RKILAFKPLTKVLFVGTGAGAGYTAYTVDSVEDLRQL-----GLLRFGRAASTVGKIVIDY---- 59

Human   180 NVVLRGVEENSPGYLEVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVL 244
            ...|||:.|.|..|.:.:..||||:|:.|:..|..|||:::|:||.:....:|:|||||:||.:|
 Worm    60 KTSLRGLPEPSSEYDDAIKKCHQRSAEHLLELACVNGGVFIKVGQHISGMEYLIPPEYTQTLSIL 124

Human   245 EDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHD-GTSVAVKVQYIDL 308
            ..:|.:...::|..:...:..|...:||.||..:|:.||||||||:|||.: |.:||||||:..:
 Worm   125 TSQAPQASKEDVIYVVESELNAKVGDLFSEFSEKPVGAASLAQVHKAKLKESGETVAVKVQHKRV 189

Human   309 RDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVV 373
            ......|::|:|.|:::.:.:.|.|...|::.::|..|..||||.:|.:||:..|:...|..::.
 Worm   190 YKNSRTDVNTMEFLVKVADAVFPEFRLMWLVDEIKKNLPNELDFLHEAKNADEAAQRFKHLKFLR 254

Human   374 VPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPG 438
            :|::.:|.::.||||.:||.|..|:|||.::...:..||:..|:.|..:|.||..|::|||||||
 Worm   255 IPKIKYDLTTTRVLTMEFCEGAHVDDVEYLKKNNIDPHDVCMKIGKTISEMIFLQGYLHSDPHPG 319

Human   439 NVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQD-YLLFA 502
            |||:....:||.|:||||||||..:.:..|.....||.||:..|...:|..|:.:||.: |.|||
 Worm   320 NVLINSLGNGKYEIVLLDHGLYLNISDHIRKLYSDLWLAILKPDLQEIRKVASQMGVGELYGLFA 384

Human   503 EMLMQRPVRLGQLW-------GSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRNINT 560
            .|:.:|.      |       |...::..|...:...|......:..||..:||.|||:|:..:.
 Worm   385 CMVTRRS------WKSVTGGIGKSKMNESEKDELRMYASSLIPQISEVLARMPREMLLILKTNDL 443

Human   561 VRAINVALG--APVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKV----VWEMLK 614
            :|.|...||  ...|.:..|::..:|....||...     ..|||...|:    .|.::|
 Worm   444 MRNIEHKLGVFGSSDGHIEMSRCVIRSSHDLAIRR-----SDSLLGKFKIGFHMYWSLMK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADCK5	XP_011515209.1	AarF	202..>482	CDD:223733	111/280 (40%)
		ADCK1-like	243..483	CDD:270871	92/240 (38%)
D2023.6	NP_505980.1	ADCK1-like	123..375	CDD:270871	95/251 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2179
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D350846at33208
OrthoFinder	1	1.000	-	-		FOG0000919
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100510
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.670